Cystic Fibrosis Center

CHOC has the only cystic fibrosis center in Orange County for kids. We provide the best CF treatments so your child lives a long, healthy life.

Rare diseases and rare opportunities

Wang moved on to CHOC, where many patients come in with a laundry list of symptoms that defy explanation.

What to Expect at Your Fetal Care Center Appointment

The specialists at the Fetal Care Center of Southern California understand every pregnancy is different. Learn what to expect at your fetal medicine appointment.

Attention Deficit Hyperactivity Disorder (ADHD)

Learn about ADHD, its signs and symptoms, treatment and medication, and tips for managing ADHD in children from CHOC mental health experts.

Fetal Diagnostic Testing

The Fetal Care Center of Southern California at CHOC offers prenatal diagnostic testing & examinations during pregnancy. See types and examples of fetal diagnostic tests and their benefits.

Fetal Echocardiogram

CHOC offers the only comprehensive fetal cardiology services in Orange County, including performing fetal echocardiograms on pregnant women.

Tuberous Sclerosis Program

CHOC is designated by the Tuberous Sclerosis Alliance to treat children with tuberous sclerosis, a rare disorder causing epilepsy and growths inside organs.

Study shows rWGS led to better outcomes for critically ill infants

CHOC participated in Project Baby Bear, a program that demonstrated the clinical and economic value of rapid Whole Genome Sequencing (rWGS).

Primary Ciliary Dyskinesia (PCD)

Primary ciliary dyskinesia (PCD) is a disease that affects the body's ability to remove mucus from the airways. Learn the causes & symptoms of PCD in children.

Researcher Profile: Dr. Afshin Aminian

Pediatric orthopaedic surgeon and researcher Afshin Aminian, MD, is driven by one goal: to “give children with movement challenges a life without limits.”

Treatment Programs

The CHOC Children's Heart Institute offers a variety of pediatric cardiac treatment programs and services.

Otolaryngology (Ear, Nose and Throat)

CHOC pediatric otolaryngology cares for children of all ages – from newborns to teens – with conditions of the ears, nose, throat (ENT), head and neck throughout Orange County, Mission Viejo, and surrounding areas.

Types of Sex Differentiation Disorders

There are many types of disorders of sexual differentiation (DSD) and atypical genitalia, and the symptoms each child experiences will vary greatly based on the type and severity of the disorder.

Understanding Disorders of Sex Differentiation

Disorders of sex differentiation, also known as disorders of sexual development or DSD, are conditions in which the sexual development that occurs during fetal growth does not happen as it should

Congenital Heart Defects: Tetralogy of Fallot

Tetralogy of Fallot (TOF or "TET") is a heart condition that occur due to abnormal development of the fetal heart. Learn more about what TOF is, its symptoms, and causes.

Fetal Care Center Referrals

Heart Conditions in Children

Heart conditions are among the most common birth defects in the United States, affecting about 1 in every 100 children. Heart conditions can be congenital (present at birth) or acquired (developed after birth).

Metabolic Rare Disease Research

At the CHOC Research Institute, our work focuses on developing treatments for children with rare conditions that do not respond to traditional treatments.

Metabolic Disorders

The CHOC Metabolic Disorder program is a multidisciplinary team committed to family-focused care for children and adults with inborn metabolic disorders

Abdenur, Jose E. MD

Dr. Abdenur is the chief of the division of metabolic disorders at CHOC and Director of CHOC's metabolic laboratory.

Wang, Raymond Y. MD

Dr. Wang is the director of multidisciplinary lysosomal storage disorder program at CHOC and a board certified clinical geneticist.

CHOC Neuroscience Institute

Ranked by U.S. News and World Report, CHOC's neurology and neurosurgery specialists treat children with conditions of the brain, spine and nervous system.

High-Risk Pregnancy

Every family looks forward to a healthy pregnancy and to the birth of a healthy newborn. For some, there may be unexpected challenges along the way because an expectant mother has a high-risk pregnancy.

Lysosomal Storage Disease Program

The Foundation of Caring Lysosomal Storage Disorder Program at CHOC is a unique treatment program for children with lysosomal storage disorders.

Phenylketonuria (PKU) Program

CHOC provides a unique multidisciplinary and comprehensive program for the diagnosis and treatment of children and teens with phenylketonuria (PKU).