CHOC at Mission Hospital

We know that all parents want the best medical care for their children, that is easily accessible and conveniently located. That’s why we offer a top children’s hospital just for south Orange County families. CHOC at Mission Hospital is a separately licensed 54-bed “hospital within a hospital” on the fifth floor of Mission Hospital. It is the only children’s hospital in south Orange County, the surrounding coastal areas and north San Diego County.

South Orange County’s Only Children’s Hospital

Inside its doors, you’ll find a modern facility with comprehensive services, individualized care and personal attention for patients ranging from newborns to young adults.

At CHOC at Mission Hospital, we offer:

  • A full medical staff, with physicians in virtually every pediatric specialty
  • An all-RN nursing staff
  • Hospitalists and neonatologists on site 24 hours a day
  • 24-bed Medical/Surgical Unit for children who need to be hospitalized while receiving care for an illness, injury or surgery.
  • 8-bed Pediatric Intensive Care Unit (PICU) providing the highest level of care for critically ill and injured children
  • 22-bed, Level 3 NICU providing critical care for newborns, and neonatal care teams who can be present during high-risk births at Mission Hospital
  • State-of-the-art Epilepsy Monitoring Unit and Sleep Center
  • Child life specialists to help minimize anxiety for young patients and their siblings, and to help them understand medical treatments
  • Pediatric emergency services and a Level II Pediatric Trauma Center
  • Ronald McDonald Family Room, sleep rooms and shower accommodations for families to stay the night with their child in the hospital
  • Additional shared services with Mission Hospital including rehabilitation services, surgical services, radiology and laboratory

Learn more about our Level 3 NICUState-of-the-art Sleep CenterLevel II Trauma Center

Stories from CHOC at Mission Hospital

Girl on skateboard
Grace's parents and teachers noticed that she had poor balance, slept a lot and would have brief periods of looking inattentive. After a stay in CHOC at Mission Hospital's Epilepsy Monitoring Unit, her family had a diagnosis.

Parents holding newborn twins
After years of trying to start a family, Breanne and Kristopher Kessler were ecstatic to learn they were expecting twins. But when Breanne was only 30 weeks pregnant, something went wrong. The team at the CHOC at Mission Hospital NICU was ready.

Dr Goodman and Michael Ramsey
One evening, while playing soccer in the dark, Michael ran into a waist-high chain and suffered a traumatic brain injury. He was rushed to CHOC at Mission Hospital and received round-the-clock care in the PICU. Eight days later, he woke up.

Contact and Directions

CHOC at Mission Hospital

CHOC at Mission Hospital is located in Mission Viejo in the heart of South Orange County, with easy access from the 5 freeway off Crown Valley Parkway and close access to the 241 Toll Road.

5th floor of Mission Hospital’s patient care tower
27700 Medical Center Rd. – 5th Floor Mission Viejo, CA 92691


Virtual Tour

Hallway at CHOC Children's Mission Hospital

Hospitals can be a scary place for children. Through its family centered care approach to treatment and recovery, CHOC at Mission Hospital tends to the emotional and practical needs of patients and their caregivers.

MyChart Patient Portal

MyChart makes it easy to get care and manage your health including checking in for your next appointment. At any time, on any device you can:

  • Message your care team
  • Manage appointments
  • View test results
  • Renew prescriptions
  • Pay bills
young baby being examined by doctor with stethoscope