Leading-edge Children’s Research
CHOC offers access to cutting-edge pediatric research and clinical trials that can't be found anywhere else.
CHOC Research - Go Beyond

CHOC Research Institute

Terence Sanger, Chief Scientific Officer at CHOC, speaks to the importance of research at a children’s hospital.

We conduct research directly with children and adolescents in a facility devoted exclusively to the care, quality of life, rights and safety of children of all ages.

At CHOC, we know that research saves lives. That’s why our Research Institute has more than 500 research studies in more than 30 specialties to provide your child with access to leading-edge treatments. Our scientists translate the latest advances in molecular profiling, including whole genome sequencing, to meet the individual needs of our patients at every stage of their young lives —from infancy through adolescence.

 

Clinical Trials

Clinical Trials

At CHOC, we are dedicated to providing patients the very latest breakthrough treatments available to children, adolescents and young adults. Our efforts bring hope to patients with rare conditions, or conditions not responding to traditional treatments.

About the CHOC Research Institute

The CHOC Research Institute was formally established in 2003, after years of active participation in pediatric clinical research. Today, the Research Institute supports more than 350 active human-subject research studies across nearly all of our pediatric subspecialty areas.

The Institute’s Sponsored Projects and Research Compliance offices administer and oversee federal NIH, California State CIRM, private foundation and donor funding in support of translational and clinical child health research.

The Research Institute also has a formal affiliation with UC Irvine, a collaboration that brings advanced treatment to patients. Through the partnership, additional grants have been awarded to both institutions, and CHOC researchers have access to valuable University resources, like the Beckman Laser Institute, in an effort to bring breakthrough therapies and cures to pediatric patients.

Research Professionals

The Research Institute is committed to delivering comprehensive service, from pre-award assistance to post-award management. We make every effort to accommodate individual researcher's needs and schedules within the resources of our office, and we act as an advocate for the faculty and the university in the research process.

Institutional Review Boards
CHOC currently has two Institutional Review Boards
Research Administration
CHOC's Research Administration office is a valuable resource for the CHOC community, providing expertise and highly specialized service in the important area of research management.
Proposal Preparation
Information you need for proposal preparation.

Stories of Innovative Pediatric Research

Patient playing Choco's Undersea Adventure AR module

CHOC’s innovation team offers solution to early ambulation challenges with augmented reality module, Choco’s Undersea Adventure.

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Child on mechanical bull. Mechanical bulls may be dangerous for kids.

A CHOC research study discovers the injury risks and safety of mechanical bull riding for kids and encourages more safety precautions.

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CHOC study wearable robots

The Research Institute at CHOC is co-leading a study on soft wearable robots with equilibrium-point control for kids with movement disorders.

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Brain scans

CHOC’s revised care guidelines for pediatric strokes aims to quickly diagnose and provide intervention for acute pediatric strokes.

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Drs. HaDoung and Plant-Fox

CHOC neuro-oncologist initiated a clinical trial to test a vaccine for DIPG, a rare and devastating cancer.

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Dr. Joffre Olaya

A CHOC neurosurgeon explains effective surgical interventions, including laser ablation, RNS and DBS for the treatment of refractory pediatric epilepsy.

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baby in NICU

CHOC’s NICU patients benefit from quality improvement initiatives to ensure consistent neonatal care and enable swift response to QI results.

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dog laying on floor

With hundreds kids being treated for dog bites each year at CHOC, experts discuss why dogs bite kids and how to prevent injury.

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Boy smiles in front of inflatable bounce house

A study by the CHOC Research Institute shows a rise in injuries caused by bounce houses. Learn how to keep your kids safe in bounce houses.

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Discover the latest advances in pediatric medicine, research and innovation.

Contact Us

 

Location: CHOC Research Building – 4th Floor

Phone: 714-509-4341 | Fax: 714-509-4318