Leading-edge Children’s Research
CHOC offers access to cutting-edge pediatric research and clinical trials that can't be found anywhere else.
CHOC Research - Go Beyond

CHOC Research Institute

Terence Sanger, Chief Scientific Officer at CHOC, speaks to the importance of research at a children’s hospital.

We conduct research directly with children and adolescents in a facility devoted exclusively to the care, quality of life, rights and safety of children of all ages.

At CHOC, we know that research saves lives. That’s why our Research Institute has more than 500 research studies in more than 30 specialties to provide your child with access to leading-edge treatments. Our scientists translate the latest advances in molecular profiling, including whole genome sequencing, to meet the individual needs of our patients at every stage of their young lives —from infancy through adolescence.

Clinical Trials

Clinical Trials

At CHOC, we are dedicated to providing patients the very latest breakthrough treatments available to children, adolescents and young adults. Our efforts bring hope to patients with rare conditions, or conditions not responding to traditional treatments.

About the CHOC Research Institute

The CHOC Research Institute was formally established in 2003, after years of active participation in pediatric clinical research. Today, the Research Institute supports more than 350 active human-subject research studies across nearly all of our pediatric subspecialty areas. The Institute’s Sponsored Projects and Research Compliance offices administer and oversee federal NIH, California State CIRM, private foundation and donor funding in support of translational and clinical child health research. The Research Institute also has a formal affiliation with UC Irvine, a collaboration that brings advanced treatment to patients. Through the partnership, additional grants have been awarded to both institutions, and CHOC researchers have access to valuable University resources, like the Beckman Laser Institute, in an effort to bring breakthrough therapies and cures to pediatric patients.

Research Professionals

The Research Institute is committed to delivering comprehensive service, from pre-award assistance to post-award management. We make every effort to accommodate individual researcher's needs and schedules within the resources of our office, and we act as an advocate for the faculty and the university in the research process.

Institutional Review Boards
CHOC currently has two Institutional Review Boards
Research Administration
CHOC's Research Administration office is a valuable resource for the CHOC community, providing expertise and highly specialized service in the important area of research management.
Proposal Preparation
Information you need for proposal preparation.

Stories of Innovative Pediatric Research

Graphic representation of artificial intelligence - a blue/green image with a white ripple effect

Students involved in CHOC’s Research Institute were on winning teams with projects utilizing AI to improve patient outcomes.

CHOC logo  CHOC Pediatrica

Up-close image of a growth plate of a bone under a microscope - CHOC

The most common type of dwarfism, achondroplasia can now be treated with Voxzogo starting at birth, maximizing children’s growth potential.

CHOC logo  CHOC Pediatrica

CHOC's innovative gene therapy infusion treatment for hemophilia

The center becomes the first in the country to administer a commercial gene therapy infusion to treat Hemophilia A, the common disorder affecting males.

CHOC logo  CHOC Pediatrica

Child uses iPad in class - What parents should know about AI

A CHOC expert explains the benefits of AI in pediatric healthcare and how it may affect the health of kids and teens.

CHOC logo  CHOC Health

Child holds autism awareness puzzle pieces

A proud CHOC mom offers lessons learned from her family’s over 20 years of experience with autism spectrum disorder.

CHOC logo  CHOC Health

Child on mechanical bull. Mechanical bulls may be dangerous for kids.

A CHOC research study discovers the injury risks and safety of mechanical bull riding for kids and encourages more safety precautions.

CHOC logo  CHOC Health

Discover the latest advances in pediatric medicine, research and innovation.

Contact Us

CHOC Clinic Building

Click on image for directions.

Location: CHOC Research Building – 4th Floor

Phone: 714-509-4341 | Fax: 714-509-4318