Leading-edge Children’s Research
CHOC offers access to cutting-edge pediatric research and clinical trials that can't be found anywhere else.

CHOC Research Institute

Terence Sanger, Chief Scientific Officer at CHOC, speaks to the importance of research at a children’s hospital.

We conduct research directly with children and adolescents in a facility devoted exclusively to the care, quality of life, rights and safety of children of all ages.

At CHOC, we know that research saves lives. That’s why our Research Institute has over 350 research studies in more than 30 specialties to provide your child with access to leading-edge treatments. Our scientists translate the latest advances in molecular profiling, including whole genome sequencing, to meet the individual needs of our patients at every stage of their young lives —from infancy through adolescence.

 

Stories of Innovative Pediatric Research

Crowd of people wearing masks

A team from CHOC has published original research on the prevalence of COVID-19 infection among its Emergency Department workers during the early stages of the pandemic. A key finding of the study, called PASSOVER (Provider Antibody Serology Study of Virus in the Emergency Room), suggests that most infections were transmitted through community exposure rather than … Continue reading Study of COVID-19 infection rates among CHOC’s Emergency Department personnel suggests most got virus through community exposure

  CHOC Docs Blog

Futuristic image of brain

Two of CHOC’s leading pediatric neurosurgeons recently shared their insights on how innovation is helping to close the gap between clinical needs and the availability of pediatric devices, but how there is much more work to be done to get critically ill kids the treatments they need. The webinar, “From Clinical Insight to Commercialization: Innovations … Continue reading Neurosurgery Institute leaders discuss innovations and their successes, and the need for much more work to be done

  CHOC Docs Blog

Father and son use tablet

A couple of years ago, Adam Gold, CHOC’s chief technology officer, started thinking about what kind of app could help parents of kids with autism – or kids with other cognitive challenges, for that matter. Gold has a nephew who has autism spectrum disorder (ASD), and his wife, Lisa, is a special education teacher.  Now, … Continue reading New app helps build daily routines for kids with autism spectrum disorder

  CHOC Docs Blog

twin sisters

When 7-year-old Naomi Adrian took a spill on the school playground earlier this year and a schoolmate fell on top of her left leg, she got up with a slight limp. After what appeared to be a bruise kept growing, and as Naomi continued to walk awkwardly, her mother, Maria Nino, took her to the […]

  CHOC Health

baby hope

Baby Hope looked into her mother’s eyes and gurgled. Four days short of turning 9 months old, wearing a white onesie with the words “Best Gift Ever” on the front, she made more baby talk. “You’re always a big chatterbox – what are you saying?” her mother, Elizabeth “Becca” Wyneken, said as she smiled and […]

  CHOC Health

CHOC patient and her father

Every morning when she awakes, Sydney Amato begins her daily battle with her body. If she’s lucky, the 16-year-old will have gotten a handful of hours of uninterrupted sleep – dreaming, perhaps, of doing what most healthy kids her age take for granted: Hanging out with friends. Going to school. Learning to drive. Because of […]

  CHOC Health