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RXDX-101-03 – A Phase 1/1b, Open-Label, Dose-Escalation and Expansion Study of Entrectinib (RXDX-101) in Children and Adolescents with Recurrent or Refractory Solid Tumors and Primary CNS Tumors, with or without TRK, ROS1, or ALK Fusions (Igny

Clinical Trial Protocol # RXDX 101 | Adolescents and Young Adults, Brain Tumor/Central Nervous System/Neuro-Oncology, Recurrent/Refractory Cancer, Solid Tumors | Contact (714) 509-8646

https://www.choc.org/clinical-trials/rxdx-101-03-a-phase-11b-open-label-dose-escalation-and-expansion-study-of-entrectinib-rxdx-101-in-children-and-adolescents-with-recurrent-or-refractory-solid-tumors-and-primary-cns-tumors-with/

Giovanetti, Caitlin A. NP

Caitlin Giovanetti is a nurse practitioner who specializes in oncology. She provides care for pediatric cancer patients at CHOC Hospital in Orange.

https://www.choc.org/providers/oncology/caitlin-a-giovanetti-np/

Pathare, Jody NP

Jody Pathare is a nurse practitioner who specializes in oncology medicine. She provides care for kids and teens with cancer at CHOC.

https://www.choc.org/providers/oncology/jody-pathare-np/

Klimpel, Lisa M NP

Lisa Klimpel is a nurse practitioner who specializes in oncology and provides care for pediatric cancer patients at CHOC Hospital in Orange.

https://www.choc.org/providers/oncology/lisa-m-klimpel-np/

Adams, Nicole E. NP

Nicole Adams is a nurse practitioner who specializes in oncology. She provides care for pediatric cancer patients at CHOC Hospital in Orange.

https://www.choc.org/providers/oncology/nicole-e-adams-np/

ADVL1515 A Phase 1 Study of LY2606368, a CHK1/2 Inhibitor, in Pediatric Patients with Recurrent or Refractory Solid Tumors, including CNS Tumors

Clinical Trial Protocol # ADVL1515 | Adolescents and Young Adults, Brain Tumor/Central Nervous System/Neuro-Oncology, Recurrent/Refractory Cancer, Solid Tumors | Contact (714) 509-8646

https://www.choc.org/clinical-trials/advl1515-a-phase-1-study-of-ly2606368-a-chk1-2-inhibitor-in-pediatric-patients-with-recurrent-or-refractory-solid-tumors-including-cns-tumors/

An Open-label, Multicenter, Phase 2 Study Evaluating the Efficacy and Safety of Daratumumab in Pediatric and Young Adult Subjects > 1 and < 30 Years of Age With Relapsed/Refractory Precursor B-cell or T-cell Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

Clinical Trial Protocol # JNJ-54767414 | Adolescents and Young Adults, Leukemia/Lymphom, Recurrent/Refractory Cancer | Contact (714) 509-8646

https://www.choc.org/clinical-trials/oncology-clinical-trials/an-open-label-multicenter-phase-2-study-evaluating-the-efficacy-and-safety-of-daratumumab-in-pediatric-and-young-adult-subjects-1-and-30-years-of-age-with-relapsed-refractory-precursor-b-cell-or/

Phase 2 Trial of XL184 (Cabozantinib) an Oral Small-Molecule Inhibitor of Multiple Kinases, in Children and Young Adults with Refractory Sarcomas, Wilms Tumor, and Other Rare Tumors

Clinical Trial Protocol # ADVL1622 | Adolescents and Young Adults, Recurrent/Refractory Cancer, Solid Tumors | Contact (714) 509-8646

https://www.choc.org/clinical-trials/phase-2-trial-of-xl184-cabozantinib-an-oral-small-molecule-inhibitor-of-multiple-kinases-in-children-and-young-adults-with-refractory-sarcomas-wilms-tumor-and-other-rare-tumors/

HaDuong, Josephine H. MD

Dr. Josephine HaDuong is a specialist in pediatric oncology. She provides care for the full spectrum of childhood cancers for kids in Orange County.

https://www.choc.org/providers/oncology/josephine-haduong-md/

English, Mary NP

Mary English is a nurse practitioner who specializes in oncology. She provides care for pediatric cancer patients at CHOC Hospital in Orange.

https://www.choc.org/providers/oncology/mary-english-np/

Oncology Clinical Trial: WEE1 Inhibitor MK-1775 and Local Radiation Therapy in Treating Younger Patients With Newly Diagnosed Diffuse Intrinsic Pontine Gliomas

Clinical Trial Protocol # ADVL1217 | Brain Tumor/Central Nervous System/Neuro-Oncology | Contact (714) 509-8646

https://www.choc.org/clinical-trials/oncology-clinical-trials/wee1-inhibitor-mk-1775-and-local-radiation-therapy-in-treating-younger-patients-with-newly-diagnosed-diffuse-intrinsic-pontine-gliomas/

Oncology Clinical Trial: A Study of Ramucirumab (LY3009806) in Children With Refractory Solid Tumors

Clinical Trial Protocol # ADVL1416 | Brain Tumor/Central Nervous System/Neuro-Oncology, Recurrent/Refractory Cancer, Solid Tumors | Contact (714) 509-8646

https://www.choc.org/clinical-trials/oncology-clinical-trials/a-study-of-ramucirumab-ly3009806-in-children-with-refractory-solid-tumors/

ADVL1721/COG/Bayer 806946/19176: A non-randomized, open-label, multi-center, Phase I/II study of PI3K inhibitor copanlisib in pediatric patients with relapsed/refractory solid tumors or lymphoma

Clinical Trial Protocol # ADVL1721 | Adolescents and Young Adults, Leukemia/Lymphoma, Recurrent/Refractory Cancer, Solid Tumors | Contact (714) 509-8646

https://www.choc.org/clinical-trials/advl1721cogbayer-80694619176-a-non-randomized-open-label-multi-center-phase-iii-study-of-pi3k-inhibitor-copanlisib-in-pediatric-patients-with-relapsedrefractory-solid-tumors-or-lymphoma/

Oncology Clinical Trial: Vincristine Sulfate Liposome Injection (Marqibo®) in Combination With UK ALL R3 Induction Chemotherapy for Children, Adolescents, and Young Adults With Relapsed ALL

Clinical Trial Protocol #T2012-002 | Adolescents and Young Adults, Leukemia/Lymphoma, Recurrent/Refractory Cancer | Contact (714) 509-8646

https://www.choc.org/clinical-trials/oncology-clinical-trials/vincristine-sulfate-liposome-injection-marqibo-in-combination-with-uk-all-r3-induction-chemotherapy-for-children-adolescents-and-young-adults-with-relapsed-all/

Oncology Clinical Trial: WEE1 Inhibitor MK-1775 and Irinotecan Hydrochloride in Treating Younger Patients With Relapsed or Refractory Solid Tumors

Clinical Trial Protocol # ADVL1312 | Adolescents and Young Adults, Brain Tumor/Central Nervous System/Neuro-Oncology, Recurrent/Refractory Cancer, Solid Tumors | Contact (714) 509-8646

https://www.choc.org/clinical-trials/oncology-clinical-trials/wee1-inhibitor-mk-1775-and-irinotecan-hydrochloride-in-treating-younger-patients-with-relapsed-or-refractory-solid-tumors/

Oncology Clinical Trial: A Phase II Study of Dasatinib Therapy in Children and Adolescents with Newly Diagnosed Chronic Phase CML or with Ph+ Leukemias Resistant or Intolerant to Imatinib

Clinical Trial Protocol # 90325 | Adolescents and Young Adults, Leukemia/Lymphoma, Recurrent/Refractory Cancer, oncology | Contact (714) 509-8646

https://www.choc.org/clinical-trials/oncology-clinical-trials/phase-ii-study-dasatinib-theraphy-children-adolescents-chronic-phase-cml-ph-leukemias-resistant-intolerant-imatinib/

Oncology Clinical Trial: Lorvotuzumab Mertansine in Treating Younger Patients With Relapsed or Refractory Wilms Tumor, Rhabdomyosarcoma, Neuroblastoma, Pleuropulmonary Blastoma, Malignant Peripheral Nerve Sheath Tumor, or Synovial Sarcoma

Clinical Trial Protocol # ADVL1522 | Recurrent/Refractory Cancer, Solid Tumors | Contact (714) 509-8646

https://www.choc.org/clinical-trials/oncology-clinical-trials/lorvotuzumab-mertansine-younger-patients-relapsed-refractory-wilms-tumor-rhabdomyosarcoma-neuroblastoma-pleuropulmonary-blastoma-malignant-peripheral-nerve-sheath-tumor-synovial-sarcoma/

Oncology Clinical Trial: Study of Selinexor in Pediatric Solid Tumors

Clinical Trial Protocol # ADVL1414 | Brain Tumor/Central Nervous System/Neuro-Oncology, Recurrent/Refractory Cancer, Solid Tumors | Contact (714) 509-8646

https://www.choc.org/clinical-trials/oncology-clinical-trials/study-of-selinexor-in-pediatric-solid-tumors/

ADVL1722/Eisai E7389G000223: A Phase 2, multicenter, open-label study to assess safety and preliminary activity of eribulin mesylate in pediatric subjects with relapsed/refractory rhabdomyosarcoma (RMS), non-rhabdomyosarcoma soft tissue sarcoma (NRSTS) an

Clinical Trial Protocol # ADVL1722 | Adolescents and Young Adults, Recurrent/Refractory Cancer, Solid Tumors | Contact (714) 509-8646

https://www.choc.org/clinical-trials/advl1722eisai-e7389g000223-a-phase-2-multicenter-open-label-study-to-assess-safety-and-preliminary-activity-of-eribulin-mesylate-in-pediatric-subjects-with-relapsedrefractory-rhabdomyosarcoma-rm/

Oncology Clinical Trial: Nivolumab With or Without Ipilimumab in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Sarcomas

Clinical Trial Protocol # ADVL1412 | Recurrent/Refractory Cancer, Solid Tumors | Contact (714) 509-8646

https://www.choc.org/clinical-trials/oncology-clinical-trials/nivolumab-with-or-without-ipilimumab-in-treating-younger-patients-with-recurrent-or-refractory-solid-tumors-or-sarcomas/

Oncology Clinical Trial: Glembatumumab Vedotin in Treating Patients With Recurrent or Refractory Osteosarcoma

Clinical Trial Protocol # AOST1521 | Recurrent/Refractory Cancer, solid Tumors | Contact (714) 509-8646

https://www.choc.org/clinical-trials/oncology-clinical-trials/glembatumumab-vedotin-in-treating-patients-with-recurrent-or-refractory-osteosarcoma/

Oncology Clinical Trial: Dinutuximab in Combination With Sargramostim in Treating Patients With Recurrent Osteosarcoma

Clinical Trial Protocol # AOST1421 | Recurrent/Refractory Cancer, Solid Tumors | Contact (714) 509-8646

https://www.choc.org/clinical-trials/oncology-clinical-trials/dinutuximab-in-combination-with-sargramostim-in-treating-patients-with-recurrent-osteosarcoma/

Oncology Clinical Trial: Collecting and Storing Samples of Bone Marrow and Blood From Patients With Relapsed Acute Lymphoblastic Leukemia or Non-Hodgkin Lymphoma

Clinical Trial Protocol # AALL05B1 | Biology/Genomics, Leukemia/Lymphoma, Recurrent/Refractory Cancer | Contact (714) 509-8646

https://www.choc.org/clinical-trials/oncology-clinical-trials/collecting-and-storing-samples-of-bone-marrow-and-blood-from-patients-with-relapsed-acute-lymphoblastic-leukemia-or-non-hodgkin-lymphoma/

Wu, Vivian NP

Vivian Wu is a nurse practitioner who provides care for kids and teens at CHOC Hospital in Orange.

https://www.choc.org/providers/oncology/vivian-wu-np/

Sato, Mariko MD

Dr. Sato is a board certified pediatric oncologist at CHOC Hospital in Orange County.

https://www.choc.org/providers/oncology/mariko-sato-md/