Dr. Richard C. Chang, Metabolic Disorders

Dr. Richard C. Chang, Metabolic Disorders

  • Richard C Chang MD
  • Appointments:
  • Office: 714-509-8852
  • Specialty: Metabolic Disorders
  • Board Certified: Medical Biochemical Genetics, Clinical Informatics
  • Additional Languages: Mandarin, Taiwanese

Dr. Chang is a member of the CHOC Specialists Metabolic Disorders division and is board certified in Medical Biochemical Genetics. Dr. Chang completed his residency training at CHOC Hospital in Orange and attended medical school at the University of Iowa School of Medicine. Dr. Chang is the assistant division chief of Metabolic Disorders at CHOC. His interests are in the presentation, diagnosis, and treatment of inborn errors of metabolism. Dr. Chang serves as a physician informaticist at CHOC Hospital where he serves as a consultant for electronic health record implementation to enhance health care delivery. Dr. Chang is an Assistant Clinical Professor with the University of California, Irvine School of Medicine. Dr. Chang speaks Mandarin Chinese and Taiwanese Chinese.

Richard C Chang MD is on staff at CHOC Hospital in Orange .

More About Dr. Chang

  • Medical School
    University of Iowa School of Medicine
  • Pediatrics Residency
    CHOC Hospital in Orange, Orange, CA
  • Assistant Clinical Professor
    University of California, Irvine, School of Medicine
  • Metabolic Disorders, CHOC Specialists
  • American Academy of Pediatrics
  • American Medical Informatics Association
  • Orange County Pediatric Society
  • Society of Inborn Metabolic Disorders

Wang RY, Chang R, Sowa M, Chang A, Abdenur JE. Prevention of metabolic decompensation in an infant with mutase deficient methylmalonic aciduria undergoing cardiac surgery requiring cardiopulmonary bypass. Submitted. World Journal of Pediatrics. Jan 2013.

Miyake N, Yano S, Sakai C, Hatakeyama H, Matsushima Y, Shiina M, Watanabe Y, Bartley J, Abdenur JE, Wang RY, Chang R, Tsurusaki Y, Doi H, Nakashima M, Saitsu H, Ogata K, Goto YI, Matsumoto N. Mitochondrial Complex III Deficiency Caused by a Homozygous UQCRC2 Mutation Presenting with Neonatal-Onset Recurrent Metabolic Decompensation. Hum Mutat. 2012 Dec 19. doi: 10.1002/humu.22257. [Epub ahead of print]

Williams TB, Daniels M, Puthenveetil G, Chang R, Wang RY, Abdenur JE. Neonatal Diabetes and Adrenal Insufficiency as early manifestations of Pearson Syndrome. Molecular Genetics and Metabolism. 2012, 106(1)104-7.

Friedman J, Roze E, Abdenur JE, Chang R, Gasperini S, Saletti V, Wali GM, Eiroa H, Neville B, Felice A, Parascandalo R, Zafeiriou DI, Arrabal-Fernandez L, Dill P, Eichler FS, Echenne B, Gutierrez-Solana LG, Hoffmann GF, Hyland K, Kusmierska K, Tijssen MAJ, Lutz T, Mazzuca M, Penzien J, Poll-The BT, Sykut-Cegielska J, Szymanska K, Thöny B, Blau N. Sepiapterin Reductase Deficiency: a treatable mimic of cerebral palsy. Annals of Neurology. 2012, 71(4):520-30.

Sass JO, Fischer K, Wang R, Christensen E, Scholl-Bürgi S, Chang R, Kapelari K, Walter M. D-glyceric aciduria is caused by genetic deficiency of D-glycerate kinase (GLYCTK). Hum Mutat. 2010 Dec;31(12):1280-5. doi: 10.1002/humu.21375.

Puckett RL, Orsini JJ, Pastores GM, Wang RY, Chang R, Saavedra-Matiz CA, Torres PA, Zeng B, Caggana M, Lorey F, Abdenur JE. Krabbe Disease: Clinical, Biochemical and Molecular Information on Six New Patients and Successful Retrospective Diagnosis Using Stored Newborn Screening Cards. Molecular genetics and Metabolism, 105 (1):126-31

Puckett R, Sowa M, Lorey F, Levine S, Rinaldo P, Lipson M, Matern D, Sowa M, Levine S, Chang R, Wang R, Abdenur JE. Maple syrup urine disease (MSUD) : Further evidence that variant forms cannot be detected by newborn screening (NBS). MGM 2010; 100: 136-142

Health Topics

Preemie nestled in adult hands
Parents and Preemies

A premature baby or preemie is born before 37 weeks of gestation. They often require hospitalization. The best way for it to grow is to have the mother's milk.


Map of CHOC Specialty Care Clinic
CHOC Specialty Care Clinic

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CHOC Health Center, Corona

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