Dr. Shireen V. Guide, Pediatric Dermatology

Dr. Shireen V. Guide, Pediatric Dermatology

  • Shireen V. Guide MD
  • Appointments:
  • Specialty: Dermatology
  • Board Certified: Dermatology, Pediatric Dermatology, Micrographic Dermatologic Surgery
  • Additional Languages: Farsi, French, Spanish

Dr. Shireen V. Guide is a triple board-certified dermatologist and a board-certified pediatric dermatology subspecialist. Dr. Guide has over 20 years of experience in the medical field and is the founder of Mission Dermatology Center. She has three board certifications: Dermatology, Pediatric Dermatology and Micrographic Dermatologic Surgery. She completed her medical education and internship at Stanford University School of Medicine (MD, 2002) and completed her dermatology residency training at the University of Texas Southwestern, followed by a fellowship in pediatric and adolescent dermatology at the University of California San Diego/ Rady Children’s Hospital.  She currently serves the communities of Orange County at her multi-location dermatology private practice as well as the Children’s Hospital of Orange County (CHOC). She serves as Assistant Clinical Professor at University of California Irvine School of Medicine. She is the Director of Pediatric Dermatology Resident Education at UCI, and also teaches pediatric residents at the CHOC hospital. Dr. Guide runs numerous pediatric clinical trials for new medications to treat both common and rare skin diseases. She was instrumental in the process of the first FDA-approved treatment for Epidermolysis Bullosa (May 2022).

Shireen V. Guide MD is on staff at CHOC Hospital in Orange .


29829 Santa Margarita Pkwy
Suite 500
Rancho Santa Margarita, CA 92688
phone: 949-858-3376
fax: 949-259-0010

1120 W. La Veta #125
Orange, CA 92868
phone: 949-858-3376
fax: 949-259-0010


  • Medical School
    Stanford University School of Medicine, Stanford, CA
  • Dermatology Residency
    University of Texas Southwestern Medical Center, Dallas, TX
  • Pediatric Dermatology Fellowship
    UCSD/Rady Children’s Hospital, San Diego, CA
  • Clinical Research Fellowship
    National Institutes of Health