Dr. Anthony C. Chang, Chief Intelligence and Innovation Officer

Dr. Chang attended Johns Hopkins University for his B.A. in molecular biology prior to entering Georgetown University School of Medicine for his M.D. He then completed his pediatric residency at Children’s Hospital National Medical Center and his pediatric cardiology fellowship at the Children’s Hospital of Philadelphia. He then accepted a position as attending cardiologist in the cardiovascular intensive care unit of Boston Children’s Hospital and as assistant professor at Harvard Medical School.

He has been the medical director of several pediatric cardiac intensive care programs (including Children’s Hospital of Los Angeles, Miami Children’s Hospital, and Texas Children’s Hospital). He served as the medical director of the Heart Institute at Children’s Hospital of Orange County.

He is currently the Chief Intelligence and Innovation Officer (CIIO) and Medical Director of the Heart Failure Program at Children’s Hospital of Orange County. He has also been named a Physician of Excellence by the Orange County Medical Association and Top Cardiologist, Top Doctor for many years as well as one of the nation’s Top Innovators in Healthcare.

He has completed a Masters in Business Administration (MBA) in Health Care Administration at the University of Miami School of Business and graduated with the McCaw Award of Academic Excellence. He also completed a Masters in Public Health (MPH) in Health Care Policy at the Jonathan Fielding School of Public Health of the University of California, Los Angeles and graduated with the Dean’s Award for Academic Excellence. He later taught Global Health there. Finally, he graduated with his Masters of Science (MS) in Biomedical Data Science with a subarea focus in artificial intelligence from Stanford School of Medicine and has completed a certification on artificial Intelligence from MIT. He is a computer scientist-in-residence and a member of the Dean’s Scientific Council at Chapman University.

He has helped to build a successful cardiology practice as a startup company and was able to complete a deal on Wall Street. He is known for several innovations in pediatric cardiac care, including introducing the cardiac drug milrinone and co-designing (with Dr. Michael DeBakey) an axial-type ventricular assist device in children. He is a committee member of the National Institute of Health pediatric grant review committee. He is the editor of several textbooks in pediatric cardiology, including Pediatric Cardiac Intensive Care, Heart Failure in Children and Young Adults, and Pediatric Cardiology Board Review.

He is the founder of the Pediatric Cardiac Intensive Care Society (PCICS) that launched the multi-disciplinary focus on cardiac intensive care for children. He is also the founder of the Asia-Pacific Pediatric Cardiac Society (APPCS), which united pediatric cardiologists and cardiac surgeons from 24 Asian countries and launched a biennial meeting in Asia that now draws over 1,000 attendees.

He is the founder and medical director of the Medical Intelligence and Innovation Institute (MI3) that is supported by the Sharon Disney Lund Foundation. The institute is dedicated to implement data science and artificial intelligence in medicine and is the first institute of its kind in a hospital. The new institute is concomitantly dedicated to facilitate innovation in children and health care all over the world. He is the organizing chair for the biennial Pediatrics2040: Emerging Trends and Future Innovations meeting as well as the founder and director of the Medical Intelligence and Innovation Summer Internship Program, which mentors close to 100 young physicians-to-be every summer. He has organized a pediatric innovation leadership group called the international Society for Pediatric Innovation (iSPI).

He intends to build a clinician-computer scientist interface to enhance all aspects of data science and artificial intelligence in health and medicine. He currently lectures widely on big data and artificial intelligence in medicine (he has been called “Dr. A.I.” by the Chicago Tribune and has given a TEDx talk as well as on the Singularity University faculty) (1). He has published review papers on big data and predictive analytics as well as machine learning and artificial intelligence in medicine (2)(3). He has completed a book project with a book series with Elsevier: Intelligence-Based Medicine: Principles and Applications of Artificial Intelligence in Clinical Medicine and Health Care and is the editor-in-chief of the journal of the same title. He is the founder and organizing chair of many Artificial Intelligence in Medicine (AI Med) meetings in the U.S. and abroad (Europe and Asia) that will focus on artificial intelligence in healthcare and medicine (www.ai-med.io). He intends to start a new group for clinicians with a special focus on data science and artificial intelligence as Medical Intelligence Society, or MIS. Finally, he is the dean of the nascent American Board of Artificial Intelligence in Medicine (ABAIM) that will have education and certification of artificial intelligence in clinical medicine and health care as its mission.

He is the founder of three startup companies in artificial intelligence in medicine:

  • CardioGenomic Intelligence (CGI), LLC is a multifaceted company that focuses on artificial intelligence applications such as deep learning in clinical cardiology (cardiomyopathy and heart failure as well as other cardiovascular disease) and genomic
  • Artificial Intelligence in Medicine (AIMed), LLC is an events company that organizes meetings and educational programs in artificial intelligence in medicine in local as well as global
  • Medical Intelligence 10 (MI10), LLC is an education and consulting/advising conglomerate for executives and physician leaders as well as investors for the evaluation and implementation of AI strategies in healthcare organizations, for evaluation and recommendation of AI in healthcare vendors, and assessment and implementation of cybersecurity in healthcare organizations.

Administrative Appointments

  • Chief Intelligence and Innovation Officer, Medical Intelligence and Innovation Institute
  • Cardiology, CHOC Children’s Specialists

Education

  • Graduate Education – M.S. (Biomedical Informatics) (in progress)
    Stanford University, Stanford, California
  • Graduate Education – M.P.H.
    University of California at Los Angeles School of Public Health, Los Angeles, California
  • Graduate Education – M.B.A (Healthcare Administration)
    University of Miami School of Business, Miami, Florida
  • Pediatric Cardiology Fellowship
    Children’s Hospital of Philadelphia, Pennsylvania
  • Pediatric Residency
    Children’s Hospital National Medical Center, Washington, DC
  • Medical School
    Georgetown University Medical School, Washington, DC

Honors and Awards

Dean’s Outstanding Scholarship Award (graduated first in class) and Delta Omega (Public Health Honor Society)
UCLA MPH Program and School of Public Health

Outstanding Teaching Award
UCLA Pediatric Cardiology Program

Professional Organizations

  • American Medical Association
  • American College of Cardiology
  • American Heart Association (Executive Vice President, Miami Chapter)
  • Society of Critical Care Medicine (scientific consultant)
  • Pediatric Cardiac Intensive Care Society (president-elect)
  • American College of Physician Executives (advanced standing)
  • American College of Healthcare Executives
  • American College of Medical Practice Management
  • American Society of Artificial Internal Organs

Primary Areas of Interest:

  • Artificial Intelligence in Clinical Medicine and Health Care
  • Innovation in Pediatric Health Care
  • Global and Public Health
  • Business and Healthcare Administration
  • Heart Failure in Children and Adults
  • Pediatric Cardiac Intensive Care

Our cardiologists commonly treat: 

  • Congenital heart defects
  • Chest pain
  • Heart murmur
  • Family history of heart disease
  • Hypertension, obesity and lipid management
  • Syncope and palpitations
  • Sports cardiology
  • Cardiac genetics
  • Cardiomyopathy
  • Chronic lung disease

Published Works

Chang AC, Morell J, Rebolledo M.
Ten Innovative Concepts for the Pediatric Cardiology Clinical Service.
Congenital Cardiology Today, May 2012.

Chang AC, Musen M.
Artificial Intelligence in Pediatric Cardiology: An Innovative Transformation
In Patient Care, Clinical Research, and Medical Education.
Congenital Cardiology Today, November 2012

Inayat M, Yeasted R, Schultz E, Cleary J, Chang A.
Bosentan Role in Severe Refractory Pulmonary Hypertension in an
Extremely Low Birth Weight Infant.

Perry J, Lanzberg M, Franklin W, Webb G, Chang A.
Cardiac Intensive Care of the Adult with Congenital Heart Disease: Basic
Principles in the Management of Common Problems.

Wang R, Covault K, Halcrow E, Gardner A, Cao X, Newcomb R, Dauben R,
Chang A.
Carotid intima-media thickness is increased in patients with
Mucopolysaccharidoses

Chang A.
Big Data in Pediatric Cardiology: The Upcoming Knowledge Revolution.
Congenital Cardiology Today, April 2013.

Locations

CHOC Children’s Specialists – Cardiology
505 S. Main Street
Suite 200
Orange, CA 92868
phone: 714-509-3939
fax: 714-509-3949

CHOC Children’s Hospital
1201 W. La Veta Ave.
Orange, CA 92868-3874

CHOC Children’s at Mission Hospital
27700 Medical Center Rd
Mission Viejo, CA 92691

Sea View Pediatrics
23521 Paseo de Valencia
Suite 200
Laguna Hills, CA 92654

Irvine Pediatrics
16300 Sand Canyon Ave
Suite 811
Irvine, CA 92618

Hoag Memorial Presbyterian Hospital
1 Hoag Drive
Newport Beach, CA 92663

Western Medical Center
1001 N Tustin Ave
Santa Ana, CA 92705

CHOC Children’s Health Center in Corona
854 Magnolia Ave
Suite 101
Corona, CA 92879

Anaheim Regional Medical Center
1111 W La Palma Ave
Anaheim, CA 92801

St Jude Medical Center
101 E Valencia Mesa Dr
Fullerton, CA 92835

PIH Health Family Practice Center
12291 Washington Blvd
Suite 500
Whittier, CA 90606

UCLA
10833 Le Conte Ave
Los Angeles, CA 90024

  • Anthony C Chang MD, MBA, MPH, MS
    • Appointments:
      888-770-2462
    • Office: 714-509-3939
    • Specialty: Cardiology
    • Board Certified: Pediatric Cardiology
    • On Staff at: CHOC Children's Hospital and CHOC Children's at Mission Hospital

Videos

Dr. Anthony Chang takes pleasure in seeing his patients grow

Being a Doctor: Dr. Chang

Being a doctor, Dr. Anthony Chang tells us about the pleasure he gets from seeing his small patients grow up to be adults.

Dr. Chang speaking about stimulants and the effects on the heart

Stimulants and the Effects on the Heart: Dr. Chang

Stimulants and the effects on the heart is the topic in this video with Dr. Anthony Chang. He tells when a medication indicates there is a stimulant inside.

Dr. Anthony Chang - increase of sudden cardiac arrest in athletes

LEAPS: Dr. Chang

Dr. Anthony Chang discusses Life-threatening Events Associated with Pediatric Patients in Sports (LEAPS) & the increase of sudden cardiac death in young athletes in O.C.

Podcasts

Spyro Mousses, Ph.D., Dr. Leonard Sender, and Dr. Anthony Chang in Seacrest Studio

Impact of Precision Medicine on Oncology Field

Precision medicine is changing how physicians think about treatments, with great advances coming out of the oncology field. In podcast No. 42, three CHOC experts and speakers at the upcoming Peds2040 conference.