All Clinical Trials:

Oncology Clinical Trial: WEE1 Inhibitor MK-1775 and Local Radiation Therapy in Treating Younger Patients With Newly Diagnosed Diffuse Intrinsic Pontine Gliomas

Clinical Trial Protocol # ADVL1217 | Brain Tumor/Central Nervous System/Neuro-Oncology | Contact (714) 509-8646

Oncology Clinical Trials Pilot Project: Harnessing big data for new ideas in pediatric, adolescent and young adult oncology

Clinical Trial Protocol # 160778 | Adolescents and Young Adults, oncology | Contact (714) 509-8646

Phase 1 Study of ABI-009 (nab-rapamycin) in Pediatric Patients with Recurrent or Refractory Solid Tumors, including CNS Tumors as a Single Agent and in Combination with Temozolomide and Irinotecan

Clinical Trial Protocol # ADVL1514 | Adolescents and Young Adults, Recurrent/Refractory Cancer, Solid Tumors | Contact (714) 509-8646

Phase 1 Study of Pevonedistat (MLN4924, IND# 136078), a NEDD8 Activating Enzyme (NAE) Inhibitor, in Combination with Temozolomide and Irinotecan in Pediatric Patients with Recurrent or Refractory Solid Tumors

Clinical Trial Protocol # ADVL1615 | Adolescents and Young Adults, Recurrent/Refractory Cancer, Solid Tumors | Contact (714) 509-8646

Phase 1/2 Study of Lenvatinib in Combination with Everolimus in Recurrent and Refractory Pediatric Solid Tumors, including CNS

Clinical Trial Protocol # ADVL1711 | Adolescents and Young Adults, Recurrent/Refractory Cancer, Solid Tumors | Contact (714) 509-8646

Phase 1/2 Study of VX15/2503 (IND# 136181) in Children, Adolescents, or Young Adults with Recurrent or Relapsed Solid Tumors

Clinical Trial Protocol # ADVL1614 | Adolescents and Young Adults, Recurrent/Refractory Cancer, Solid Tumors | Contact (714) 509-8646

Phase 2 Trial of XL184 (Cabozantinib) an Oral Small-Molecule Inhibitor of Multiple Kinases, in Children and Young Adults with Refractory Sarcomas, Wilms Tumor, and Other Rare Tumors

Clinical Trial Protocol # ADVL1622 | Adolescents and Young Adults, Recurrent/Refractory Cancer, Solid Tumors | Contact (714) 509-8646

Phase II open-label global study to evaluate the effect of dabrafenib in combination with trametinib in children and adolescent patients with BRAF V600 mutation positive relapsed or refractory High Grade Glioma (HGG)

Clinical Trial Protocol # CDRB436G2201 | Adolescents and Young Adults, Brain Tumor/Central Nervous System/Neuro-Oncology, Recurrent/Refractory Cancer, Solid Tumors | Contact (714) 509-8646

RXDX-101-03 – A Phase 1/1b, Open-Label, Dose-Escalation and Expansion Study of Entrectinib (RXDX-101) in Children and Adolescents with Recurrent or Refractory Solid Tumors and Primary CNS Tumors, with or without TRK, ROS1, or ALK Fusions (Igny

Clinical Trial Protocol # RXDX 101 | Adolescents and Young Adults, Brain Tumor/Central Nervous System/Neuro-Oncology, Recurrent/Refractory Cancer, Solid Tumors | Contact (714) 509-8646

TINI, Total Therapy For Infants with Acute Lymphoblastic Leukemia (ALL) I

Clinical Trial Protocol # TINI | Leukemia | Contact (714) 509-8646

​AALL15P1 A Groupwide Pilot Study to Test the Tolerability and Biologic Activity of the Addition of Azacitidine (IND# 133688, NSC# 102816) to Chemotherapy in Infants with Acute Lymphoblastic Leukemia (ALL) and KMT2A Gene Rearrangement.

Clinical Trial Protocol # AALL15P1 | Leukemia | Contact (714) 509-8646

​ACNS1422 A Phase 2 Study of Reduced Therapy for Newly Diagnosed Average-Risk WNT-Driven Medulloblastoma Patients

Clinical Trial Protocol # ACNS1422 | Brain Tumor/Central Nervous System/Neuro-Oncology | Contact (714) 509-8646

​ADVL1521 A Phase 2 Study of the MEK inhibitor Trametinib (IND#119346, NSC#763093) in Children with Relapsed or Refractory Juvenile Myelomonocytic Leukemia

Clinical Trial Protocol # ADVL1521 | Leukemia | Contact (714) 509-8646

​AHEP1531, Pediatric Hepatic Malignancy International Therapeutic Trial (PHITT)

Clinical Trial Protocol # AHEP1531 | Solid Tumors | Contact (714) 509-8646

​Testicular Tissue Cryopreservation for Fertility Preservation in Patients Facing Infertility-causing Diseases or Treatment Regimens

Clinical Trial Protocol - Testicular Cryopreservation | Contact (714) 509-8646