CHOC Blood Bank

CHOC relies on volunteer blood donors like you, your friends, neighbors and co-workers to meet the needs of our patients. Every time our volunteers donate, they leave knowing they are having direct impact on the recovery of a child. Your blood donation gives children a better chance at a healthy life.

With the support of our community we have been able to supply 50 percent of our patients’ needs for blood transfusions, a percentage that we would love to increase. Donor recruitment is always challenging and we want to assure our blood and platelet inventory remains robust. Please call the Blood Donor Center at 714- 509-8339 to make an appointment. Walk-ins are always welcome.

Coordinate a Blood Drive

Coordinating a blood drive is one of the best ways to support your community. Get together with your friends, work, school, church, service organization or anyone else and we will reserve time at our center specifically for your group. Coordinating a blood drive is easy to do, takes very little effort and produces big life-saving results. For more information or to set up a blood drive, fill out an inquiry here, or call 714-509-8339.

As of now, we do not conduct mobile blood drives. All blood drives will take place exclusively at our Orange, CA location. 

Designated Donor Program

CHOC also offers a unique designated donor program which allows your blood donation to be directed to a specific child in need. Each unit of blood is tested and if accepted and compatible will be available for the specific child. No blood is ever wasted and if the donation is not compatible or the child does not need the blood at the time, it will be released to another child in need. Blood donations must be received at least four days before the child’s anticipated need. Families can set up a designated donor program by calling 714-509-8339 and then begin recruiting donors.

About Blood Donations

Young boy in hospital bed

What blood types are needed?

We are currently in need of Type O and Type B blood types. Don’t know what type of blood you have? Come in and donate and we can find out for you a few days after your donation. Your valuable support can make a significant difference in the lives of these children.

Is donating blood safe?

There is no danger in getting AIDS or other diseases from giving blood or blood products. Sterile, one-time-use disposable needles, tubing and collection bags are used to protect you. Registered nurses who are specially trained in blood collection will remain with you during the entire donation process.

Are there any side effects?

Side effects as the result of blood donation are rare. The donor center nursing staff will educate you on any potential side effects that you could possibly experience. Healthy people have an excess supply of red blood cells, platelets and plasma.

Blood Donor Requirements & Preparation

Blood donors must:
  • Be in good health
  • Be at least 17 years old
  • Weigh at least 110 pounds
  • Have no history of hepatitis or AIDS
  • Have no history of chest pain or cardiac surgery
On the day of donation, blood donors must:
  • Bring a photo ID to the donor center
  • Be free of cold and flu symptoms
  • Eat a good meal within three hours of donating
  • Have medications and medical conditions reviewed by the donor center staff
  • Not have taken any aspirin, aspirin products or ibuprofen within 48 hours of donating platelets
When you come to donate:
  • We will ask you questions about your medical history
  • We will check your temperature, pulse, blood pressure and blood count for anemia
  • Highly trained medical staff and nurses collect the blood product from your arm while you watch television, see a video, read a book or just relax
  • You will be given post-donation instructions and refreshments before you leave

National Blood Donor Month: Mackenzie's Story

Before Mackenzie was born, prenatal ultrasounds and testing diagnosed her with TAR syndrome, a rare genetic disorder that meant she was missing a bone in each forearm and had a dramatically low platelet count. Doctors also detected a heart defect that would require surgery immediately after she was born. Over the next three years, she received nearly 200 blood and platelet donations. Now every time Mackenzie has an appointment at CHOC, she stops by the Blood & Donor Services Center with her mom to personally thank donors for helping kids just like her.

Smiling toddler girl with pink bow in her hair in front of tree

Make an Appointment

Same-day appointments are often available.

We are located in the CHOC Commerce Tower.
505 S. Main St. Suite 185
Orange, CA 92868

Blood Donation Interest
To make an appointment, you can call 714-509-8339, or email

Blood and Donor Services Hours:
Monday and Wednesday – 7 a.m. to 5 p.m.
Tuesday and Thursday – 10 a.m. to 8 p.m.
Friday – 8 a.m. to 6 p.m.
Saturday – Closed
Sunday – Closed

Bone Marrow Information:
e-mail: or call 1-800-627-7692

505 S. Main St

Click on image for directions.