Children's Hospital of Orange County (CHOC) has made a commitment to both basic science and clinical research in an ongoing effort to unravel the complex underpinnings of diseases that affect children. This commitment keeps CHOC at the leading edge of technology, meaning children seen at CHOC benefit from the latest in scientific thinking with access to the most up-to-date treatment options. Research laboratories at CHOC support a variety of basic science, translational, and clinical research studies.
- Institutional Review Boards
CHOC currently has three Institutional Review Boards (IRBs)
- Research Administration
CHOC’s Research Administration office is a valuable resource for the CHOC community, providing expertise and highly specialized services in the important area of research management.
- Research Faculty
Information about the CHOC Children's Research Institute faculty.
- Proposal Preparation
Information you need for proposal preparation.
Dr. Nugent - Why Research Matters
In this video, Chief of Hematology Dr. Diane Nugent talks about the research that goes on at CHOC Children's and how this research helps children in our community.
Dr. Diane Nugent, Medical Director, Hematology
Dr. Diane Nugent reveals that CHOC is able to launch tecnology not available anywhere else in the United states for monitoring sick children.
Genomic Cancer Research: Dr. Sender - No Place Like CHOC
Leonard Sender M.D., Medical Director of the Hyundai Cancer Institute at CHOC Children's, talks about clinical trials for cancer patients.
Dr. Phil Schwartz, Director of National Human Neural Stem Cell Research
Phil Schwartz, PhD, speaks about using stem cell research to understand the disease of autism.
Hyundai Donation - Hope on Wheels
Hope On Wheels and Hyundai Motor America presented the second installment of a $10 million commitment to CHOC Children’s to fund groundbreaking cancer research at the Hyundai Cancer Institute at CHOC Children’s.
CHOC Children’s adopts new genome sequencing service
August 15, 2012
The service is part of a study to improve pediatric cancer treatment.
New Study to Explore Efficacy of Narcotics in Managing Kids’ Pain
August 15, 2012
Hyundai Cancer Institute at CHOC Children’s is First to Utilize Illumina’s RapidTrack Whole Genome Sequencing Service For Cancer Study
August 13, 2012
As part of a pilot study designed to advance personalized treatment for children and teens battling recurrent cancer, the Hyundai Cancer Institute at CHOC Children’s is the first organization to utilize Illumina’s RapidTrack Whole Genome Sequencing (RapidTrack WGS) service for cancer samples.
Articles From the Blog:
CHOC Using Stem Cells To Study Impact Of Autism
Wed, 01 Sep 2010 02:35:39 GMT
Last year, CHOC Children’s Research Institute received a National Institutes of Health (NIH) Research Grant to generate, investigate, and store neural stem cells derived from skin cells, donated by children with autism. The program is designed to provide an important new tool for studying the impact of autism on the developing brain. Check out what
Why Research Matters
Sat, 21 Aug 2010 05:51:19 GMT
Watch as Diane Nugent, MD, tells us how the research happening at CHOC Children’s is changing screening and treatment for childhood disease. And not just in Orange County–across the country. Learn more about the CHOC Children’s Research Institute.
CHOC Research Institute Makes a Mark
Wed, 11 Aug 2010 07:25:17 GMT
CHOC Research Institute Associate Ryan Roberts is working with a team of scientists to identify specific genetic markers for Sickle Cell Disease and Thalassemia . By carefully studying the genetic origins of pediatric disease, he is helping to pioneer new screenings and treatments for red cell abnormalities. To learn more about The CHOC Research Institute,
Our Research Institute is REALLY Cool
Sat, 07 Aug 2010 05:56:40 GMT
Watch as the Director of CHOC Research Institute Brent Dethlefs shows off some of the “cool” equipment we’ve got in our state-of-the-art research labs here at the hospital. Scientists at the CHOC Research Institute use cryogenic freezers to store donated cord blood and bone marrow to be used for transplants in patients with oncology or
National Children’s Study Underway in Orange County
Wed, 04 Aug 2010 00:39:36 GMT
University of California, Irvine, in partnership with CHOC Children’s, the Children and Families Commission of Orange County and the Orange County Health Care Agency, was selected to conduct the National Children’s Study – the largest and most comprehensive long-term study of environmental effects on child development and health. Since last October, more than 20 babies
Articles From the CHOC Docs Blog:
Curiosity Drives Infectious Diseases Research
Thu, 20 Sep 2012 23:39:24 GMT
A CHOC Children’s investigator-initiated trial into neonates with necrotizing enterocolitis (NEC) has discovered key microbial and survival differences in patients who develop blood stream infections. These findings may help explain why premature infants with intestinal pathology experience more complications and higher mortality rates. CHOC Infectious Diseases Medical Director Antonio Arrieta, M.D., and his team have [...]