Children's Hospital of Orange County (CHOC) has made a commitment to both basic science and clinical research in an ongoing effort to unravel the complex underpinnings of diseases that affect children. This commitment keeps CHOC at the leading edge of technology, meaning children seen at CHOC benefit from the latest in scientific thinking with access to the most up-to-date treatment options. Research laboratories at CHOC support a variety of basic science, translational, and clinical research studies.
- Institutional Review Boards
CHOC currently has two Institutional Review Boards (IRBs)
- Research Administration
CHOC’s Research Administration office is a valuable resource for the CHOC community, providing expertise and highly specialized services in the important area of research management.
- Research Faculty
Information about the CHOC Children's Research Institute faculty.
- Proposal Preparation
Information you need for proposal preparation.
Dr. Nugent - Why Research Matters
In this video, Chief of Hematology Dr. Diane Nugent talks about the research that goes on at CHOC Children's and how this research helps children in our community.
Hyundai Donation - Hope on Wheels
Hope On Wheels and Hyundai Motor America presented the second installment of a $10 million commitment to CHOC Children’s to fund groundbreaking cancer research at the Hyundai Cancer Institute at CHOC Children’s.
Genomic Cancer Research: Dr. Sender, CHOC Children's
In this segment of American Health Journal, Dr. Leonard Sender, Medical Director of Hyundai Cancer Insititute at CHOC Children's, explains genomic cancer research and how identifying the specific medicines that work on a child's disease is a challenge.
Autism Research: Dr. Schwartz, CHOC Children's
In this segment of American Health Journal, Dr. Phil Schwartz, CHOC Children's, explains how autism is currently is being diagnosed and how new new research may lead to diagnosing the disorder with a simple blood test.
Genomic Cancer Research: Dr. Sender - No Place Like CHOC
Leonard Sender M.D., Medical Director of the Hyundai Cancer Institute at CHOC Children's, talks about clinical trials for cancer patients.
First Stem Cell Production Facility to Focus on Immune-Matching Therapies Opens at CHOC
August 05, 2014
A new stem cell production facility at Children’s Hospital of Orange County will allow researchers to produce patient-specific cells for future immune-matching therapies that could positively impact fatal neurological diseases in children.
New Innovation in the AYA Cancer Movement: The Future Is Here
January 15, 2014
SAYAO held their first annual conference at the University of California, Irvine (UC Irvine), in partnership with the Hyundai Cancer Institute at the Children's Hospital of Orange County (CHOC Children's).
Advances in the Young Adult Cancer Movement: Why Sayao Is a Big Deal
December 16, 2013
SAYAO was envisioned and developed under the leadership of Dr. Leonard Sender, a pediatric and adult Hematologist/Oncologist.
Articles From the Blog:
Research Leads to More Gratitude
Wed, 27 Aug 2014 17:00:54 GMT
As my 50-week gratitude tour for all things CHOC Children’s nears its end, I’d be remiss if I didn’t point out how grateful I am for the research that happens at CHOC. CHOC is committed to clinical research and understanding the mysteries behind childhood diseases. Because of this, CHOC patients have access to current treatment
Thu, 24 Jul 2014 22:44:41 GMT
In this CHOC Radio segment, Dr. Antonio Arrieta discusses proper timing of vaccinations, dispels myths surrounding vaccinations, and details his current research at CHOC. Listen in to hear more about childhood vaccinations.
CHOC Psychologist Discusses Pain in Children
Mon, 19 May 2014 22:01:06 GMT
It’s a misconception that children always outwardly express pain, and when they do, it’s often accomplished verbally and behaviorally. Children experiencing pain may also exhibit changes in sleep patterns and eating habits, and may appear withdrawn. Listen to learn more about pain in children, including how parents respond to pain, how different cultures view pain, and how to manage pain in children.
The Institutional Review Board’s Role in Research
Thu, 15 May 2014 17:00:58 GMT
By Mellisa Henry, director of marketing, CHOC Children’s As the marketing director at CHOC Children’s, I have a lot of different opportunities to participate in committees that may seem out of the normal marketing realm. One of the most interesting is having a seat on our Institutional Review Board (IRB) for clinical research. Clinical research
Infectious Disease Clinical Trials at CHOC
Tue, 13 May 2014 17:00:51 GMT
Clinical trials involving real patients help doctors and researchers learn the effectiveness of a new drug or medical device, and lead to advancements with potential to improve thousands of lives. At any time, CHOC Children’s staff doctors, nurses and others are involved in about 300 clinical trials in many specialties, says Dr. Antonio Arrieta, director
Articles From the CHOC Docs Blog:
CHOC Stem Cell Production Facility to Accelerate Research into Rare Neurological Diseases
Thu, 22 May 2014 16:30:09 GMT
CHOC Children’s new stem cell production facility, slated to open late this summer, will allow CHOC researchers to produce patient-specific cells for immune-matching therapies that could positively impact fatal neurological diseases in children – all at a fraction of the cost of building a larger, more complex laboratory. Within the state-the-art softwall clean room, CHOC […]
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Dr. Philip Schwartz Discusses Autism Research
Thu, 27 Feb 2014 10:00:12 GMT
Researchers are studying autism, a brain disease, by turning skin cells into brain cells through genetic manipulation, Philip Schwartz, Ph.D., a senior scientist at CHOC Children’s Research Institute, tells “American Health Journal.” Scientists are using these cells with a goal to develop drug therapies for autism, as well as a diagnostic tool for the disorder, […]
New Technique Reduces Post-Surgery Pain in Children
Mon, 16 Dec 2013 20:32:15 GMT
CHOC Children’s researchers have identified a new technique that significantly decreases pain and the need for pain medication in children following high-risk urology surgeries, a finding that was recently published in the “Journal of Pediatric Urology.” “While pain management is a fundamental part of pediatric surgical recovery and care for pediatric patients, current options involve […]
The post New Technique Reduces Post-Surgery Pain in Children appeared first on CHOC Docs Blog.
Curiosity Drives Infectious Diseases Research
Thu, 20 Sep 2012 23:39:24 GMT
A CHOC Children’s investigator-initiated trial into neonates with necrotizing enterocolitis (NEC) has discovered key microbial and survival differences in patients who develop blood stream infections. These findings may help explain why premature infants with intestinal pathology experience more complications and higher mortality rates. CHOC Infectious Diseases Medical Director Antonio Arrieta, M.D., and his team have […]