Dr. Elyssa Rubin, Pediatric Oncology

Dr. Elyssa Rubin, Pediatric Oncology

  • Elyssa Rubin MD
  • Appointments:
  • Specialty: Oncology
  • Board Certified: Pediatrics, Hematology, Pediatric Hematology/Oncology

With special interests in sarcomas, neuroblastoma and the histocytic disorders, Dr. Elyssa Rubin serves as the director of the Bone and Soft Tissue Tumor Program at CHOC Hospital and is an oncologist with CHOC Specialists.

Dr. Rubin is board certified in pediatrics and pediatric hematology/oncology. Dr. Rubin completed her medical school training at the Sackler School of Medicine, NY State/American Branch in Tel Aviv, Israel. She completed her pediatric internship and residency training at Kaiser Permanente Los Angeles Medical Center and her fellowship in pediatric hematology/oncology at CHOC Hospital in Orange. As a research fellow, Dr. Rubin’s focus was on new therapeutic targets for osteosarcoma.

Clinical Interests

Sarcomas and the histiocytic disorders

Elyssa Rubin MD is on staff at CHOC Hospital in Orange .


Outpatient Clinic, Hyundai Cancer Institute at CHOC
1201 W. La Veta Avenue
Orange, CA 92868
phone: 714-509-8636
fax: 714-509-8699


  • Medical School
    Sackler School of Medicine, NY State/American Branch, Tel Aviv, Israel
  • Pediatric Internship and Residency
    Kaiser Permanente Los Angeles Medical Center, Los Angeles, CA
  • Fellowship
    Pediatric Hematology and Oncology at CHOC Hospital, Orange, CA

Academic Appointments

  • Assistant Professor of Pediatrics
    University of California, Irvine, School of Medicine

Administrative Appointments

  • Director, Bone and Soft Tissue Tumor Program, CHOC Hyundai Cancer Institute
  • Oncology, CHOC Specialists

Professional Organizations

  • American Association for Cancer Research (AACR)
  • American Society for Blood and Marrow Transplantation (ASBMT)
  • American Society of Clinical Oncology (ASCO)
  • American Society of Pediatric Hematology and Oncology (ASPHO)
  • Children’s Oncology Group (COG)
  • Connective Tissue Oncology Society (CTOS)
  • Histiocyte Association of America (HAA)


Buchbinder, D., Hsieh, L., Puthenveetil G., Soni A., Stites J., Huynh V., Kirov I., Neudorf S., Rubin E., Sender L., Torno L., Margolis D., Childs R., Moore T., Nugent D. Successful Autologous cord blood transplantation in a child with acquired severe aplastic anemia. Pediatr Transplant, 2013 May;17(3):E104-7. Doi: 10.1111/petr.12068. Epub 2013 Mar 7.

McQueen P, Ghaffar S, Guo Y, Rubin EM, Zi X, Hoang BH. The Wnt signaling pathway: implications for therapy in osteosarcoma. Expert Review of Anticancer Therapy. 11(8):1223-32 (2011). PMID 21916576

Rubin EM, Guo Y, Tu K, Xie J, Zi X, Hoang BH. Wnt inhibitory factor 1decreases tumorigenesis and metastasis in osteosarcoma, Mol Cancer Ther. 2010 Mar:9(3):731-41. Epub 2010 Mar 2. PMID: 20197388