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Dr. William G. Loudon, Pediatric Neurosurgery

On the forefront of pediatric neurosurgery research for more than 20 years, Dr. Loudon has conducted studies investigating molecular characterization and novel therapeutic approaches for central nervous system malignancy, cancer stem cell biology and regenerative medicine.

A respected expert in pediatric neurosurgery, Dr. Loudon’s clinical focus is in brain tumors, and is an integral member of the brain tumor program at CHOC Children’s Neuroscience Institute and the Hyundai Cancer Institute at CHOC Children’s. As part of the CHOC concussion team, Dr. Loudon is conducting clinical research into the diagnosis and treatment of pediatric concussion and head injury. He also has a patent pending on novel ex vivo three-dimensional culture system for stem cell research.

Dedicated to clinical excellence, Dr. Loudon is board certified in neurosurgery. He attended medical school at the University of Texas at Houston and received his PhD in cancer biology from University of Texas, M.D. Anderson Cancer Center. Dr. Loudon performed his pediatric neurosurgical residency at Medical College of Virginia and his postdoctoral fellowship at Massey Cancer Institute/Medical College of Virginia. He served his pediatric neurosurgery fellowship at University of Pennsylvania/Children’s Hospital of Philadelphia.

Research Focus

Molecular characterization and novel therapeutic approaches for CNS malignancy, cancer stem cell biology, regenerative medicine


CHOC Children’s Specialists – Neurosurgery
1010 W La Veta Ave #710
Orange, CA 92868
phone: 714-509-7070
fax: 714-509-7074

Administrative Appointments

  • Neurosurgeon, CHOC Children’s Neuroscience Institute
  • Neurosurgeon, The Hyundai Cancer Institute at CHOC Children’s
  • Neurosurgery, CHOC Children’s Specialists


  • Fellowship
    Pediatric neurosurgery fellowship at University of Pennsylvania/Children’s Hospital of Philadelphia
  • Medical School
    University of Texas at Houston
  • Residency
    Pediatric neurosurgical residency at Medical College of Virginia

Honors and Awards

  • Orange County Medical Association’s Physicians of Excellence 2010-2012


Li SC, Han YP, Dethlefs BA, Loudon WG. Therapeutic window, a critical developmental stage for stem cell therapies. Curr Stem Cell Res Ther. 2010 Dec 1;5(4):297-3.

Li SC, Tachiki LM, Luo J, Dethlefs BA, Chen Z, Loudon WG. A biological global positioning system: considerations for tracking stem cell behaviors in the whole body. Stem Cell Rev. 2010 Jun;6(2):317-33. Review.

Li SC, Wang L, Jiang H, Acevedo J, Chang AC, Loudon WG. Stem cell engineering for treatment of heart diseases: potentials and challenges. Cell Biol Int. 2009 Mar;33(3):255-67. Epub 2008 Dec 3. Review.

Our neurosurgeons commonly treat:

  • William G Loudon MD, PhD
    • Appointments:
    • Specialty: Neurosurgery
    • Board Certified: Neurosurgery
    • On Staff at: CHOC Children's Hospital and CHOC Children's at Mission Hospital


Dr. William Loudon - Brain Tumor

When a Child Has a Brain Tumor

Dr. William Loudon discusses the symptoms of brain tumors in children and the innovative and minimally invasive ways CHOC is treating them.

Dr. William Loudon - Craniosynostosis

When a Child Has Craniosynostosis

Dr. William Loudon explains a minimally invasive surgery used to treat mild craniosynostosis in children as well as treatment for complex craniosynostosis.

Long Live Childhood

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