Dr. Delma Nieves, Pediatric Infectious Disease

Delma Nievas, M.D. is board certified in general pediatrics and pediatric infectious diseases and began her work at CHOC in 2010. She earned her medical degree from the University of Washington. She did her pediatric residency at CHOC and postdoctoral fellowship in pediatric infectious diseases at the Mattel Children’s Hospital.

Clinical Interests

Infectious diseases of the newborn and the immuno-compromised, a-typical presentations of disease

Research Focus



CHOC Clinic
1201 W. La Veta Ave. Building: CHOC Clinic
Orange, California 92868
phone: 888-770-2462
fax: 855-246-2329

CHOC Health Center – Mission Viejo
26691 Plaza Suite 130
Mission Viejo, CA 92691


  • Medical School
    University of Washington School of Medicine, Seattle, WA
  • Pediatrics Residency
    CHOC Hospital, Orange, CA
  • Infectious Disease Fellowship
    David Geffen School of Medicine at UCLA/Mattel Children’s Hospital, Los Angeles, CA

Academic Appointments

  • Clinical Professor, Pediatrics
    UC Irvine School of Medicine

Administrative Appointments

  • Infectious Disease, CHOC Specialists

Book Chapters

Cherry JD and Nieves, DJ, The Common Cold: Feigin and Cherry’s Textbook of Pediatric Infectious Diseases, RD Feigin and JD Cherry (editors), 6th edition, W.B. Saunders Co, Philadelphia, PA, April 2009.

Nieves, DJ, Heininger U, and Cherry J Bordetella pertussis and Other Bordetella sp Infections: Remington and Klein’s Infectious Diseases of the Fetus and Newborn Infant, 8e. pending publication.

Nieves, DJ. Leptospirosis: Feigin and Cherry’sTextbook of Pediatric Infectious Diseases, JD Cherry and GJ Harrison (editors), 7th edition, Eslevier Saunders Co, Philadelphia, PA, 2014.

Lectures and Presentations

Oral presentation: Infectious Disease links to Chronic Fatigue and Fibromyalgia. Combined pediatric and adult infectious disease conference, UCLA medical center, Los Angeles, CA, May 14th, 2009

Oral presentation: Update on Leptospirosis. Combined pediatric and adult infectious disease conference, UCLA medical center, Los Angeles, CA, September 10th, 2009

Grand rounds presentations: Leptospirosis and Leptospira: the inside story, Mattel Children’s Hospital UCLA, Los Angeles, CA, July 10th, 2009

Poster Presentation: Leptospiral intracellular infection of hepatocytes in vivo and in vitro. Delma J. Nieves, MD, David R. Blanco, PhD, Thomas Ganz, MD, Julia Goodnough, Michael A. Lovett, MD, PhD. David Geffen School of Medicine UCLA, Department of Medi

Grand rounds presentation: Pertussis, CHOC Hospital, Orange, CA, March 24th, 2010

Poster presentation: Clinical and Laboratory Features of Pertussis During a California Epidemic. Singh J, Ashouri N, Nieves, D, Mcguire T, Arrieta A. 50th Interscience Conference on Antimicrobial Agents and Chemotherapy. Boston, September 12-15, 2010

Poster presentation: Safety of Micafungin in Infants less than 90 days of age. Nieves DJ, Ashouri N, Adler-Shohet F, Singh J, Arrieta A. Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) September 9-12, 2012 San Francisco, CA

Grand rounds presentation: Group B Streptococcal Infections in Neonates and Early Infancy. Parkview Hospital, Riverside, CA, November 27th, 2012

Poster presentation: Exchange Transfusion in the Management of Severe Pertussis in Young Infants. D Nieves, EL Murray, JS Bradley, J Gargas, WH Mason, D Lehman, S Lehman, K Harriman, JD Cherry. 2013 Pediatric Academic Societies’ Annual Meeting, May 4-7, i

Grand rounds presentation: Neonatal Group A Streptotoccal Infections and Osteomyelitis Review. St Bernadine Medical Center, San Bernadino, CA, May 17, 2013

Poster presentation: Increasing ESBL Infections in Children- an Emerging Pediatric Challenge? J Singh, W Gornick, N Ashouri, D Nieves. ID Week, October 2-6, 2013. San Francisco, CA

Resident Noon Conference Lecture: Prevention and Management of Intravascular Catheter Infections April 8th, 2009

Various teaching lectures for medical students/residents/fellows on a variety of pediatric infectious disease topics including “GI Infections”, “Enterovirus”, “Respiratory Viruses”, “Zoonosis”, “Periorbital/Orbital Infections”, “Infectious Diarrhea”

Peer Reviewed Articles

D Nieves, JS Bradley, J Gargas, WH Mason, D Lehman, SM Lehman, EL Murray, K Harriman, JD Cherry Exchange Blood Transfusion in the Management of Severe Pertussis in Young Infants. The Pediatric Infectious Disease Journal 2013 Jun;32(6):698-9

EL Murray, D Nieves, JS Bradley, WH Mason, D Lehman, K Harriman, JD Cherry Characteristics of Severe Bordetella pertussis Infection Among Infants
Nieves D, Arrieta A. Recent Studies on Invasive Fungal Diseases in Children and Adolescents: an Update. Accepted for publication. Curr Fungal Infect Rep. (2014) 8:56-66

Nieves D, Singh J, Ashouri N, Arrieta A, McGuire T, Adler-Shohet F. Clinical and laboratory features of pediatric pertussis disease at the onset of a California epidemic. J. Pediatr 2011, September 16.

Nieves DJ, Cnop M, Retzlaff B, Walden CE, Brunzell JD, Knopp RH, Khan SE: The Atherogenic Lipoprotein Profile Associated With Obesity and Insulin Resistance Is Largely Attributable to Intra-Abdominal Fat. Diabetes. 2003 January; 52(1): pages 172-179.

Professional Organizations

  • American Academy of Pediatrics
  • American Society for Microbiology
  • Infectious Diseases Society of America
  • Pediatric Infectious Disease Society
  • Society for Pediatric Research


Cherry JD and Nieves, DJ, The Common Cold: Textbook of Pediatric Infectious Diseases, RD Feigin and JD Cherry (editors), 6th edition, W.B. Saunders Co, Philadelphia, PA, April 2009.

Research Bio

Dr. Nieves’ clinical interests include infectious diseases of the newborn and the immuno-compromised, with special focus on fungal infections, infantile pertussis, resistant bacterial organisms, and invasive pneumococcal disease. Currently, she is engaged in a multicenter pertussis clinical research and a variety of drug trials to determine the correct antibiotic dosing and indication for pediatric patients.

Our infectious disease specialists commonly treat:

  • Infectious diseases, including those caused by multi-resistant bacteria
  • Congenital and perinatal infections, including HIV
  • Opportunistic infections in the immunocompromised patient
  • Immunocompromised host
  • Respiratory infections
  • Viral and fungal infections
  • Recurrent fever or fever of unknown origin
  • Hepatitis A, B, C delta, E and G, as well as non-A – G
  • Tuberculosis and Lyme disease
  • Coccidiomycosis and other endemic fungal infections
  • Travel medicine for children

  • Delma Nieves MD
    • Appointments:
    • Office: 714-509-8403
    • Specialty: Infectious Disease
    • Board Certified: Pediatrics, Pediatric Infectious Disease
    • Additional Languages: Spanish
    • On Staff at: CHOC Hospital in Orange and CHOC at Mission Hospital

Health Topics

Learning the good habit of washing your hands

Kids and Germs

Germs are everywhere, especially as we head into the cold and flu season. Learn how you can protect your kids from harmful bugs so they will not get sick.