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Dr. Nick G. Anas, Physician-in-Chief

A recognized expert in pediatric critical care medicine, Dr. Nick Anas has served as director of CHOC’s pediatric intensive care unit (PICU) since 1991 and as its pediatrician-in-chief since 2009. As director of the pediatric critical care program, Dr. Anas has built a team that treats children with acute, life-threatening illnesses and injuries. Dr. Anas has committed his career to developing and maintaining a critical care program at CHOC defined by clinical excellence, an uncompromising drive to provide state-of-the-art medicine for the children of Orange County, and a national reputation for leadership in academics and research.

Dr. Anas is a highly regarded leader who has served as a member of the CHOC Board of Directors and presently is a member of several boards, including CHOC Children’s Specialists, the CHOC Health Alliance and the Orange County Ronald McDonald House. Dr. Anas is a clinical professor of pediatrics in the department of pediatrics, David Geffen School of Medicine at UCLA, and is an associate clinical professor of pediatrics at UC Irvine School of Medicine.

A nationally recognized expert in the treatment of acute respiratory failure in children, Dr. Anas is an active member in the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI), an international research consortium. CHOC’s PICU is a research center for a number of clinical trials addressing issues pertinent to critical illness and injury. On the forefront of critical care education and research, Dr. Anas has more than 80 publications in prestigious medical journals and is the author and editor of several textbooks devoted to pediatric critical care. He has received numerous teaching awards from UCI-CHOC residents and CHOC critical care fellows.

Dr. Anas completed his critical care and pulmonary medicine fellowship training at the University of Rochester School of Medicine following his pediatric residency and chief residency training at Dallas Children’s Medical Center, Southwestern School of Medicine. He received his medical degree from West Virginia University and his undergraduate education at Duke University. Dr. Anas is a member of many professional organizations, including the American Academy of Pediatrics (AAP), the Society of Critical Care Medicine, the American Thoracic Society and the AOA Honor Medical Society. He also serves on the editorial board of Pediatric Critical Care Medicine, the leading journal in his discipline. A recipient of numerous honors and awards, Dr. Anas was named the 2014 Pediatrician of the Year from the California Chapter 4 (Orange County) AAP. He is also consistently named one of Orange County’s Physicians of Excellence by the Orange County Medical Association. Dr. Anas feels a strong personal responsibility to the children and parents of Orange County.


CHOC Children’s Hospital
1201 W. La Veta Ave.
Orange, CA 92868

CHOC Children’s at Mission Hospital
27700 Medical Center Rd
Mission Viejo, CA 92691

Hoag Memorial Presbyterian Hospital
1 Hoag Dr
Newport Beach, CA 92663

  • Nick G Anas MD
    • Office: 714-509-8620
    • Specialties: Critical Care, Pulmonology, Administrative
    • Board Certified: Pediatric Critical Care, Pediatric Pulmonology, Pediatrics
    • On Staff at: CHOC Children's Hospital and CHOC Children's at Mission Hospital

More About Dr. Anas

Physician-In-Chief, CHOC Children’s
Senior Vice President, CHOC Children's
Medical Director, Pediatric Intensive Care Unit, CHOC Children’s
Chair, Critical Care Medicine, CHOC Children's
Critical Care, CHOC Children’s Specialist
Associate Clinical Professor, Pediatrics
UC Irvine

Clinical Professor, Pediatrics
David Geffen School of Medicine, UCLA
Medical School
West Virginia University, Morgantown, W Virginia

Medical School - Intern
Pediatrics, Univ. of Texas Southwestern Medical School

Medical School - Resident
Pediatrics Univ. of Texas Southwestern Medical School

Postdoctoral Fellow in Pediatric Pulmonology and Critical Care
University of Rochester, School of Medicine, Rochester, New York
2014 Pediatrician of the Year
California Chapter 4 (Orange County) American Academy of Pediatrics (AAP)

The Best Doctors in Orange County
Multiple years

UCLA Pediatric Board Review
Course Lecturer

The Best Doctors in America
Multiple years

CHOC Housestaff Teaching Award
Multiple years

Editorial Board, Pediatric Critical Care
Multiple years
American Academy of Pediatrics
American Thoracic Society
California Thoracic Society
Society of Critical Care Medicine
Orange County Medical Association
Journal of Pediatrics
Pediatric Pulmonology
Critical Care Medicine
Pediatric Critical Care Medicine
British Medical Journal
Randolph A, Guo CY, Anas N et al: Vitamin D deficiency is associated with mortality in patients admitted to the pediatric intensive care unit with community acquired influenza infection. JAMA (accepted for publication)

Perkin R, Anas N: Pulmonary artery catheters Pediatr Crit Care Med 2011; 12 (4): 512-20.

Wong H, Cvijonovich N, Anas N et al: Validation of a gene expression-based subclassification strategy for pediatric septic shock. Crit Care Med 2011; 39: 2511-2517.

Randolph A, Vaughn F, Anas N et al: Critically ill children during the 2009-2010 Influenza Pandemic in the United States. Pediatrics 2011; 39: 2511-2517.

Wynn J, Cvijonovich N, Anas N et al: The influence of developmental age on the early transcriptomic response of children with septic shock. Mol Med 2011; 1146-1156.

Kline A, Sorce L, Levin D, Anas N: Pulmonary Disorders in Nursing Care of the Critically Ill Child Hazinski M (Ed). Elsevier USA 2012; 483-561.

Domico M, Ridout D, Bronicki R, Anas N et al: The impact of mechanical ventilation time before initiation of extracorporeal life support on survival in pediatric respiratory failure: A review of the extracorporeal life support registry. Pediatr Crit Care Med 2012: 13:16-21.

Basu R, Stendage S, Anas N et al: Identification of candidate serum biomarkers for severe septic shock “ associated kidney injury via microarray. (Submitted for publication).

Wong H, Salibury S, Cvijanovich N et al: The pediatric sepsis biomarker risk model. Critical Care 2012. 16:174
Pediatrician-in-Chief “ Children’s Hospital of Orange County and UCI Irvine Department of Pediatrics 2009.

Pulmonary artery catheters: State of the art. Pediatric Cardiac Intensive Care Society 2010

Pediatric representative to the Sepsis Advisory Committee. Society of Critical Care Medicine 2010.

Appointed to Editorial Board: Pediatric Critical Care Medicine 2010.

Cardiopulmonary Interactions: Pediatric Critical Care Board Review Course 2011.

President, Children’s Specialty Care Coalition Board of Directors 2012.

Board of Directors, Orange County Ronald McDonald House 2012.

“The responsibility of the CHOC Children’s critical care program is to make sure our parents sleep knowing that we are here to keep their children safe and in good health.” —Dr. Nick Anas

More About Dr. Anas and Critical Care

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UC Irvine

CHOC Children's is affiliated with the UC Irvine School of Medicine