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85 results

An Open-label, Multicenter, Phase 2 Study Evaluating the Efficacy and Safety of Daratumumab in Pediatric and Young Adult Subjects > 1 and < 30 Years of Age With Relapsed/Refractory Precursor B-cell or T-cell Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

Clinical Trial Protocol # JNJ-54767414 | Adolescents and Young Adults, Leukemia/Lymphom, Recurrent/Refractory Cancer | Contact (714) 509-8646

https://www.choc.org/clinical-trials/oncology-clinical-trials/an-open-label-multicenter-phase-2-study-evaluating-the-efficacy-and-safety-of-daratumumab-in-pediatric-and-young-adult-subjects-1-and-30-years-of-age-with-relapsed-refractory-precursor-b-cell-or/

Oncology Clinical Trial: A Multi-Center Study Evaluating KTE-C19 in Pediatric and Adolescent Subjects With Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia

Clinical Trial | Adolescents and Young Adults, Leukemia/Lymphoma, Recurrent/Refractory Cancer | Contact (714) 509-8646

https://www.choc.org/clinical-trials/oncology-clinical-trials/a-multi-center-study-evaluating-kte-c19-in-pediatric-and-adolescent-subjects-with-relapsedrefractory-b-precursor-acute-lymphoblastic-leukemia/

Pediatric Leukemia Treatment Program

CHOC Pediatric Leukemia Treatment Program with experts in all types of leukemia cancers, including very high-risk ALL and acute AML. We also offer a blood and marrow transplant program.

https://www.choc.org/cancer/leukemia-treatment-program/

Oncology Clinical Trial: Caspofungin Acetate or Fluconazole in Preventing Invasive Fungal Infections in Patients With Acute Myeloid Leukemia Who Are Undergoing Chemotherapy

Clinical Trial Protocol # ACCL0933 | Leukemia/Lymphoma, Supportive Care | Contact (714) 509-8646

https://www.choc.org/clinical-trials/oncology-clinical-trials/caspofungin-acetate-or-fluconazole-in-preventing-invasive-fungal-infections-in-patients-with-acute-myeloid-leukemia-who-are-undergoing-chemotherapy/

Oncology Clinical Trial: Risk-Based Classification System of Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

Clinical Trial Protocol # AALL08B1 | Biology/Genomics, Leukemia/Lymphoma | Contact (714) 509-8646

https://www.choc.org/clinical-trials/oncology-clinical-trials/risk-based-classification-system-of-patients-with-newly-diagnosed-acute-lymphoblastic-leukemia/

Oncology Clinical Trial: Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic Lymphoma

Clinical Trial Protocol # AALL0932 | Leukemia/Lymphoma | Contact (714) 509-8646

https://www.choc.org/clinical-trials/oncology-clinical-trials/risk-adapted-chemotherapy-in-treating-younger-patients-with-newly-diagnosed-standard-risk-acute-lymphoblastic-leukemia-or-localized-b-lineage-lymphoblastic-lymphoma/

Oncology Clinical Trial: Combination Chemotherapy With or Without Bortezomib in Treating Younger Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or Stage II-IV T-Cell Lymphoblastic Lymphoma

Clinical Trial Protocol # AALL1231 | Leukemia/Lymphoma | Contact (714) 509-8646

https://www.choc.org/clinical-trials/oncology-clinical-trials/combination-chemotherapy-with-or-without-bortezomib-in-treating-younger-patients-with-newly-diagnosed-t-cell-acute-lymphoblastic-leukemia-or-stage-ii-iv-t-cell-lymphoblastic-lymphoma/

Oncology Clinical Trial: Tretinoin and Arsenic Trioxide in Treating Patients With Untreated Acute Promyelocytic Leukemia

Clinical Trial Protocol # AAML1331 | Leukemia/Lymphoma | Contact (714) 509-8646

https://www.choc.org/clinical-trials/oncology-clinical-trials/tretinoin-and-arsenic-trioxide-in-treating-patients-with-untreated-acute-promyelocytic-leukemia/

TINI, Total Therapy For Infants with Acute Lymphoblastic Leukemia (ALL) I

Clinical Trial Protocol # TINI | Leukemia | Contact (714) 509-8646

https://www.choc.org/clinical-trials/tini-total-therapy-for-infants-with-acute-lymphoblastic-leukemia-all-i/

AALL1631 International Phase 3 Trial in Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Ph+ ALL Testing Imatinib in Combination with Two Different Cytotoxic Chemotherapy Backbones

Clinical Trial Protocol # AALL1631 | Leukemia | Contact (714) 509-8646

https://www.choc.org/clinical-trials/aall1631-international-phase-3-trial-in-philadelphia-chromosome-positive-acute-lymphoblastic-leukemia-ph-all-testing-imatinib-in-combination-with-two-different-cytotoxic-chemotherapy-backbones/

Oncology Clinical Trial: Collecting and Storing Samples of Bone Marrow and Blood From Patients With Relapsed Acute Lymphoblastic Leukemia or Non-Hodgkin Lymphoma

Clinical Trial Protocol # AALL05B1 | Biology/Genomics, Leukemia/Lymphoma, Recurrent/Refractory Cancer | Contact (714) 509-8646

https://www.choc.org/clinical-trials/oncology-clinical-trials/collecting-and-storing-samples-of-bone-marrow-and-blood-from-patients-with-relapsed-acute-lymphoblastic-leukemia-or-non-hodgkin-lymphoma/

Oncology Clinical Trial: Bortezomib and Sorafenib Tosylate in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

Clinical Trial Protocol # AAML1031 | Leukemia/Lymphoma | Contact (714) 509-8646

https://www.choc.org/clinical-trials/oncology-clinical-trials/bortezomib-and-sorafenib-tosylate-in-treating-patients-with-newly-diagnosed-acute-myeloid-leukemia/

Oncology Clinical Trial: Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down Syndrome

Clinical Trial Protocol #: AAML1531 | Leukemia/Lymphoma | Contact (714) 509-8646

https://www.choc.org/clinical-trials/oncology-clinical-trials/response-based-chemotherapy-in-treating-newly-diagnosed-acute-myeloid-leukemia-or-myelodysplastic-syndrome-in-younger-patients-with-down-syndrome/

Oncology Clinical Trial: Blinatumomab in Treating Younger Patients With Relapsed B-cell Acute Lymphoblastic Leukemia

Clinical Trial Protocol # AALL1331 | Leukemia/Lymphoma, Recurrent/Refractory Cancer | Contact (714) 509-8646

https://www.choc.org/clinical-trials/oncology-clinical-trials/blinatumomab-in-treating-younger-patients-with-relapsed-b-cell-acute-lymphoblastic-leukemia/

Oncology Clinical Trial: Gastrointestinal Microbe Population Changes in Newly Diagnosed Pediatric Pre-B Acute Lymphoblastic Leukemia Patients

Clinical Trial | Biology/Genomics, Leukemia/Lymphoma | Contact (714) 509-8646

https://www.choc.org/clinical-trials/oncology-clinical-trials/gastrointestinal-microbe-population-changes-in-newly-diagnosed-pediatric-pre-b-acute-lymphoblastic-leukemia-patients/

Understanding Leukemia in Children and Teens

Pediatric oncologist Dr. Ivan Kirov discusses leukemia in children and teens, symptoms to look for, how it is treated.

https://www.choc.org/video/understanding-leukemia-children-teens/

Oncology Clinical Trial: Study of response of lymphomas and leukemias to standard chemotherapies in patients with Biallelic Mismatch Repair Deficiencies (BMMRD)

Clinical Trial | Biology/Genomics, Leukemia/Lymphoma | Contact (714) 509-8646

https://www.choc.org/clinical-trials/oncology-clinical-trials/study-of-response-of-lymphomas-and-leukemias-to-standard-chemotherapies-in-patients-with-biallelic-mismatch-repair-deficiencies-bmmrd/

Oncology Clinical Trial: A Phase II Study of Dasatinib Therapy in Children and Adolescents with Newly Diagnosed Chronic Phase CML or with Ph+ Leukemias Resistant or Intolerant to Imatinib

Clinical Trial Protocol # 90325 | Adolescents and Young Adults, Leukemia/Lymphoma, Recurrent/Refractory Cancer, oncology | Contact (714) 509-8646

https://www.choc.org/clinical-trials/oncology-clinical-trials/phase-ii-study-dasatinib-theraphy-children-adolescents-chronic-phase-cml-ph-leukemias-resistant-intolerant-imatinib/

ADVL1521 A Phase 2 Study of the MEK inhibitor Trametinib (IND#119346, NSC#763093) in Children with Relapsed or Refractory Juvenile Myelomonocytic Leukemia

Clinical Trial Protocol # ADVL1521 | Leukemia | Contact (714) 509-8646

https://www.choc.org/clinical-trials/%e2%80%8badvl1521-a-phase-2-study-of-the-mek-inhibitor-trametinib-ind119346-nsc763093-in-children-with-relapsed-or-refractory-juvenile-myelomonocytic-leukemia/

AALL1521, A Phase 2 Study of the JAK1/JAK2 Inhibitor Ruxolitinib With Chemotherapy in Children With De Novo High-Risk CRLF2-Rearranged and/or JAK PathwayMutant Acute Lymphoblastic Leukemia

Clinical Trial Protocol # AALL1521 | Adolescents and Young Adults, Leukemia | Contact (714) 509-8646

https://www.choc.org/clinical-trials/aall1521-a-phase-2-study-of-the-jak1jak2-inhibitor-ruxolitinib-with-chemotherapy-in-children-with-de-novo-high-risk-crlf2-rearranged-andor-jak-pathwaymutant-acute-lymphoblastic-leukemia/

Oncology Clinical Trial: Combination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk B Acute Lymphoblastic Leukemia and Ph-Like TKI Sensitive Mutations

Clinical Trial Protocol # AALL1131 | Leukemia/Lymphoma | Contact (714) 509-8646

https://www.choc.org/clinical-trials/oncology-clinical-trials/combination-chemotherapy-in-treating-young-patients-with-newly-diagnosed-high-risk-b-acute-lymphoblastic-leukemia-and-ph-like-tki-sensitive-mutations/

Oncology Clinical Trial: A Study on Drug Monitoring of Asparaginase Activity in Pediatric Patients with Acute Lymphoblastic Leukemia

Clinical Trial | Biology/Genomics, Leukemia/Lymphoma | Contact (714) 509-8646

https://www.choc.org/clinical-trials/oncology-clinical-trials/a-study-on-drug-monitoring-of-asparaginase-activity-in-pediatric-patients-with-acute-lymphoblastic-leukemia/

Acute Lymphoblastic Leukemia (ALL)

Acute lymphoblastic leukemia (ALL) or acute leukemia is the most common type of childhood cancer. Read about the causes, symptoms and treatments for ALL.

https://www.choc.org/cancer/leukemia-treatment-program/acute-lymphoblastic-leukemia/

AALL15P1 A Groupwide Pilot Study to Test the Tolerability and Biologic Activity of the Addition of Azacitidine (IND# 133688, NSC# 102816) to Chemotherapy in Infants with Acute Lymphoblastic Leukemia (ALL) and KMT2A Gene Rearrangement.

Clinical Trial Protocol # AALL15P1 | Leukemia | Contact (714) 509-8646

https://www.choc.org/clinical-trials/%e2%80%8baall15p1-a-groupwide-pilot-study-to-test-the-tolerability-and-biologic-activity-of-the-addition-of-azacitidine-ind-133688-nsc-102816-to-chemotherapy-in-infants-with-acute-lymphoblastic-l/

Oncology Clinical Trial: Vincristine Sulfate Liposome Injection (Marqibo®) in Combination With UK ALL R3 Induction Chemotherapy for Children, Adolescents, and Young Adults With Relapsed ALL

Clinical Trial Protocol #T2012-002 | Adolescents and Young Adults, Leukemia/Lymphoma, Recurrent/Refractory Cancer | Contact (714) 509-8646

https://www.choc.org/clinical-trials/oncology-clinical-trials/vincristine-sulfate-liposome-injection-marqibo-in-combination-with-uk-all-r3-induction-chemotherapy-for-children-adolescents-and-young-adults-with-relapsed-all/