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Oncology Clinical Trial: Maintenance Chemotherapy or Observation Following Induction Chemotherapy and Radiation Therapy in Treating Younger Patients With Newly Diagnosed Ependymoma
Clinical Trial Protocol # ACNS0831 | Brain Tumor/Central Nervous System/Neuro-Oncology | Contact (714) 509-8646
Oncology Clinical Trial: Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma
Clinical Trial Protocol # ACNS0332 | Brain Tumor/Central Nervous System/Neuro-Oncology | Contact (714) 509-8646
Phase I/IIa, 2-Part, Multi-Center, Single-Arm, Open-Label Study to Determine the Safety, Tolerability and Pharmacokinetics of Oral Dabrafenib in Pediatric Subjects Aged 1 Month to < 18 Years with Advance BRAF V600-Mutation Positive Solid Tumors
Clinical Trial Protocol # GSK Dabrafenib | Brain Tumor/ Centra Nervous System/Neuro-Oncology, Solid Tumors | Contact (714) 509-8646
ADVL1513, A Phase 1 Study of Entinostat, an Oral Histone Deacetylase Inhibitor, in Pediatric Patients with Recurrent or Refractory Solid Tumors, including CNS Tumors and Lymphoma
Clinical Trial Protocol # ADVL1513 | Adolescents and Young Adults, Brain Tumor/Central Nervous System/Neuro-Oncology, Recurrent/Refractory Cancer, Solid Tumors | Contact (714) 509-8646
RXDX-101-03 – A Phase 1/1b, Open-Label, Dose-Escalation and Expansion Study of Entrectinib (RXDX-101) in Children and Adolescents with Recurrent or Refractory Solid Tumors and Primary CNS Tumors, with or without TRK, ROS1, or ALK Fusions (Igny
Clinical Trial Protocol # RXDX 101 | Adolescents and Young Adults, Brain Tumor/Central Nervous System/Neuro-Oncology, Recurrent/Refractory Cancer, Solid Tumors | Contact (714) 509-8646
Phase II open-label global study to evaluate the effect of dabrafenib in combination with trametinib in children and adolescent patients with BRAF V600 mutation positive relapsed or refractory High Grade Glioma (HGG)
Clinical Trial Protocol # CDRB436G2201 | Adolescents and Young Adults, Brain Tumor/Central Nervous System/Neuro-Oncology, Recurrent/Refractory Cancer, Solid Tumors | Contact (714) 509-8646
HeadStart4: Newly Diagnosed Children (<10 y/o) With Medulloblastoma and Other CNS Embryonal Tumors
Clinical Trial Protocol # Head Start IV | Brain Tumor/Central Nervous System/Neuro-Oncology | Contact (714) 509-8646
Epilepsy and Seizures in Children
Read about epilepsy in children along with diagnosis methods and different types of seizures. Learn about the different treatment options we offer at CHOC.
Epilepsy Surgery
What does epilepsy surgery mean for your child? Read everything about brain surgery for epilepsy at CHOC Neuroscience Institute.
Moyamoya Disease
What is Moyamoya? Learn more about Moyamoya brain disease in children, including information about diagnosis, symptoms, treatment, surgery and more.
Syncope (Fainting) in Children
Syncope is a temporary loss of consciousness and muscle tone caused by inadequate blood supply to the brain. Syncope is commonly called fainting.
Stem Cell Research for Kids
The CHOC Research Institute conducts leading-edge stem cell research for kids. Learn about the treatments, programs, and clinical trials at CHOC.
Neuroscience Research
CHOC neurologists research a full spectrum of pediatric disorders related to brain, spine, muscle, central and peripheral nervous systems.
Football & Concussion: Worth the Risk?
concussion rates for children under age 19 who play tackle football have doubled over the last decade, most occurring during practices.
Dystonia: What It Is, Symptoms, Types and Treatment
Dystonia is a movement disorder that can affect children of all ages. Learn what it is, how it’s diagnosed and its symptoms, causes and treatment.
Hydrocephalus
What is hydrocephalus? Read everything about hydrocephalus in children: treatment, causes, symptoms and more.
Sharing My Story With Patients
This is why I tell my story. I want them to know they are not alone on this journey. After all, for the rest of my life, I will be both a physician and a patient.
Neuronal Ceroid Lipofuscinoses (NCL)
Learn about the types of neuronal ceroid lipofuscinoses (NCLs), such as Batten disease, symptoms and diagnosis from the experts at CHOC.
Americans growing more concerned about head injuries in football
A new HealthDay/Harris Poll finds that vast majorities of Americans say football teams need to do more to protect their players from head injuries.
What This Doctor Realized When She Became the Patient
As a pediatric epileptologist, Dr. Mary Zupanc has devoted her life to understanding, preventing and treating seizures in children.
One Family’s Journey to Overcome Epilepsy
We found the Epilepsy Support Network of Orange County, which led us to Children's Hospital of Orange County Neuroscience Institute.
Teen shares story of her epilepsy journey for awareness month
An Orange County teenager shares her journey with epilepsy and how the CHOC Neuroscience Institute helped.
RIVERSIDE: Daughter’s recovery thrills mom
Riverside mother is thankful her daughter survived brain tumor removal seven years ago - “It's so amazing she could go through all that and be such a strong, happy little girl.”
First Stem Cell Production Facility to Focus on Immune-Matching Therapies Opens at CHOC
A new stem cell production facility at Children’s Hospital of Orange County (CHOC) will allow researchers to produce patient-specific cells for future immune-matching therapies that could positively impact fatal neurological diseases in children.
Parent Advice Line
To use PAL, simply call (714) 912-8927, enter the four-digit topic numbers listed on this web page, or stay on the line for a complete listing of topics.
