Oncology Clinical Trial: Collecting and Storing Blood and Brain Tumor Tissue Samples From Children With Brain Tumors

Clinical Trial Protocol # ACNS02B3 | Biology/Genomics, Brain Tumor/Central Nervous System/Neuro-Oncology | Contact (714) 509-8646

Brain Tumors in Children

Brain tumors in children can be complex. At CHOC, a multidisciplinary approach offers all services our patients need under one roof.

Clowns do more than lift spirits at children’s hospitals, they change brains

With medical clown visits, it's not just about children. Spreading happiness is good for adults as well, especially parents struggling with a child in the hospital.

Deep Brain Stimulation (DBS) Surgery in Children

What is Deep Brain Stimulation Surgery? Learn about DBS Surgery for children: how it works, risks, side effects, and more.

Traumatic Brain Injury (TBI)

Brain and Spine Tumors Program

The pediatric Brain and Spine Tumors Program at the Hyundai Cancer Institute at CHOC is a team of highly trained, multidisciplinary neuro-oncology specialists.

Arachnoid Cysts and Other Brain Cysts

Most arachnoid cysts can be monitored with no intervention, but if they grow too large, treatment becomes necessary. Read more here.

Pediatric Brain Tumor – A Molecular Era

Virtual Pediatric Lecture Series- Pediatric Oncology: Management of patient with pediatric brain tumors in maintenance and survivorship.

When a Child Has a Brain Tumor

Dr. William Loudon discusses the symptoms of brain tumors in children and the innovative and minimally invasive ways CHOC is treating them.

Is it a Brain Tumor? Dr. Taraman

Dr. Sharief Taraman, CHOC, tells us what type of condition could mimic a brain tumor and what are the syptoms that patients can experience.

When a Child has a Low-Grade Glioma (Brain Tumor)

Dr. Ashley Plant, pediatric oncologist, discusses what a low-grade glioma, also known as a brain tumor, is and how it’s treated.

Oncology Clinical Trial: WEE1 Inhibitor MK-1775 and Local Radiation Therapy in Treating Younger Patients With Newly Diagnosed Diffuse Intrinsic Pontine Gliomas

Clinical Trial Protocol # ADVL1217 | Brain Tumor/Central Nervous System/Neuro-Oncology | Contact (714) 509-8646

ADVL1615, A Phase 1 Study of Pevonedistat (MLN4924, IND# 136078), a NEDD8 Activating Enzyme (NAE) Inhibitor, in Combination with Temozolomide and Irinotecan in Pediatric Patients with Recurrent or Refractory Solid Tumors

Clinical Trial Protocol # ADVL1615 | Adolescents and Young Adults, Brain Tumor/Central Nervous System/Neuro-Oncology, Recurrent/Refractory Cancer, Solid Tumors | Contact (714) 509-8646

​ACNS1422 A Phase 2 Study of Reduced Therapy for Newly Diagnosed Average-Risk WNT-Driven Medulloblastoma Patients

Clinical Trial Protocol # ACNS1422 | Brain Tumor/Central Nervous System/Neuro-Oncology | Contact (714) 509-8646

Oncology Clinical Trial: Study of Selinexor in Pediatric Solid Tumors

Clinical Trial Protocol # ADVL1414 | Brain Tumor/Central Nervous System/Neuro-Oncology, Recurrent/Refractory Cancer, Solid Tumors | Contact (714) 509-8646

Oncology Clinical Trial: A Multi-Center Study Evaluating KTE-C19 in Pediatric and Adolescent Subjects With Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia

Clinical Trial | Adolescents and Young Adults, Leukemia/Lymphoma, Recurrent/Refractory Cancer | Contact (714) 509-8646

Oncology Clinical Trial: Molecular Profiles of Refractory and Recurrent Childhood, Adolescent, and Young Adult Cancers

Clinical Trial | Adolescents and Young Adults, Biology/Genomics, Brain Tumor/Central Nervous System/Neuro-Oncology, Leukemia/Lymphoma, Recurrent/Refractory Cancer, Solid Tumors | Contact (714) 509-8646

Oncology Clinical Trial: WEE1 Inhibitor MK-1775 and Irinotecan Hydrochloride in Treating Younger Patients With Relapsed or Refractory Solid Tumors

Clinical Trial Protocol # ADVL1312 | Adolescents and Young Adults, Brain Tumor/Central Nervous System/Neuro-Oncology, Recurrent/Refractory Cancer, Solid Tumors | Contact (714) 509-8646

Oncology Clinical Trial: A Study to Determine Safety, Tolerability and Pharmacokinetics of Oral Dabrafenib In Children and Adolescent Subjects

Clinical Trial | Solid Tumors | Contact (714) 509-8646

Oncology Clinical Trial: Comparison of Radiation Therapy Regimens in Combination With Chemotherapy in Treating Young Patients With Newly Diagnosed Standard-Risk Medulloblastoma

Clinical Trial Protocol # ACNS0331 | Brain Tumor/Central Nervous System/Neuro-Oncology | Contact (714) 509-8646

Oncology Clinical Trial: Chemotherapy Followed by Radiation Therapy in Treating Younger Patients With Newly Diagnosed Localized Central Nervous System Germ Cell Tumors

Clinical Trial Protocol # ACNS1123 | Brain Tumor/Central Nervous System/Neuro-Oncology | Contact (714) 509-8646

Oncology Clinical Trial: Maintenance Chemotherapy or Observation Following Induction Chemotherapy and Radiation Therapy in Treating Younger Patients With Newly Diagnosed Ependymoma

Clinical Trial Protocol # ACNS0831 | Brain Tumor/Central Nervous System/Neuro-Oncology | Contact (714) 509-8646

Oncology Clinical Trial: A Study of Ramucirumab (LY3009806) in Children With Refractory Solid Tumors

Clinical Trial Protocol # ADVL1416 | Brain Tumor/Central Nervous System/Neuro-Oncology, Recurrent/Refractory Cancer, Solid Tumors | Contact (714) 509-8646

Oncology Clinical Trial: Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma

Clinical Trial Protocol # ACNS0332 | Brain Tumor/Central Nervous System/Neuro-Oncology | Contact (714) 509-8646

RXDX-101-03 – A Phase 1/1b, Open-Label, Dose-Escalation and Expansion Study of Entrectinib (RXDX-101) in Children and Adolescents with Recurrent or Refractory Solid Tumors and Primary CNS Tumors, with or without TRK, ROS1, or ALK Fusions (Igny

Clinical Trial Protocol # RXDX 101 | Adolescents and Young Adults, Brain Tumor/Central Nervous System/Neuro-Oncology, Recurrent/Refractory Cancer, Solid Tumors | Contact (714) 509-8646