Leading-edge Children’s Research
CHOC offers access to cutting-edge pediatric research and clinical trials that can't be found anywhere else.
CHOC Research - Go Beyond

CHOC Research Institute

Terence Sanger, Chief Scientific Officer at CHOC, speaks to the importance of research at a children’s hospital.

We conduct research directly with children and adolescents in a facility devoted exclusively to the care, quality of life, rights and safety of children of all ages.

At CHOC, we know that research saves lives. That’s why our Research Institute has more than 500 research studies in more than 30 specialties to provide your child with access to leading-edge treatments. Our scientists translate the latest advances in molecular profiling, including whole genome sequencing, to meet the individual needs of our patients at every stage of their young lives —from infancy through adolescence.

Clinical Trials

Clinical Trials

At CHOC, we are dedicated to providing patients the very latest breakthrough treatments available to children, adolescents and young adults. Our efforts bring hope to patients with rare conditions, or conditions not responding to traditional treatments.

About the CHOC Research Institute

The CHOC Research Institute was formally established in 2003, after years of active participation in pediatric clinical research. Today, the Research Institute supports more than 350 active human-subject research studies across nearly all of our pediatric subspecialty areas.

The Institute’s Sponsored Projects and Research Compliance offices administer and oversee federal NIH, California State CIRM, private foundation and donor funding in support of translational and clinical child health research.

The Research Institute also has a formal affiliation with UC Irvine, a collaboration that brings advanced treatment to patients. Through the partnership, additional grants have been awarded to both institutions, and CHOC researchers have access to valuable University resources, like the Beckman Laser Institute, in an effort to bring breakthrough therapies and cures to pediatric patients.

Research Professionals

The Research Institute is committed to delivering comprehensive service, from pre-award assistance to post-award management. We make every effort to accommodate individual researcher's needs and schedules within the resources of our office, and we act as an advocate for the faculty and the university in the research process.

Institutional Review Boards
CHOC currently has two Institutional Review Boards
Research Administration
CHOC's Research Administration office is a valuable resource for the CHOC community, providing expertise and highly specialized service in the important area of research management.
Proposal Preparation
Information you need for proposal preparation.

Stories of Innovative Pediatric Research

Karley, cancer patient at CHOC, received the support she needed from CHOC's rehab team

With help from CHOC rehabilitation services, Karley has made strides in her development even during intense cancer treatment.

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Young child smiles while brushing her teeth, look right into the camera, wearing yellow

A CHOC mental health experts offers tips to parents to help their kids stay focused, stay on task and improve executive functioning.

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The backs of two sisters wearing life vests sitting on the dock of the lake

CHOC experts answer water safety questions about jelly fish stings, rip currents, drowning, life vests and more.

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Dr. Shaul with a patient in the hospital

A former CHOC patient born with imperforate anus offers support to families as the Colorectal and Urogenital Program grows.

CHOC logo  CHOC Pediatrica

Graphic depiction of Tcells

CHOC researchers seek to study the role of Tregs in whether pediatric leukemia patients treated with CAR T-cell therapy experience a relapse.

CHOC logo  CHOC Pediatrica

Dr. John Schlecter, orthopedic surgeon at CHOC, and looking a a teenage male patient's knee

CHOC is pioneering surgical approaches to patellofemoral instability and patellar dislocation, as well as postsurgical pain mitigation.

CHOC logo  CHOC Pediatrica

Discover the latest advances in pediatric medicine, research and innovation.

Contact Us

CHOC Clinic Building

Click on image for directions.

Location: CHOC Research Building – 4th Floor

Phone: 714-509-4341 | Fax: 714-509-4318