Leading-edge Children’s Research
CHOC offers access to cutting-edge pediatric research and clinical trials that can't be found anywhere else.
CHOC Research - Go Beyond

CHOC Research Institute

Terence Sanger, Chief Scientific Officer at CHOC, speaks to the importance of research at a children’s hospital.

We conduct research directly with children and adolescents in a facility devoted exclusively to the care, quality of life, rights and safety of children of all ages.

At CHOC, we know that research saves lives. That’s why our Research Institute has more than 500 research studies in more than 30 specialties to provide your child with access to leading-edge treatments. Our scientists translate the latest advances in molecular profiling, including whole genome sequencing, to meet the individual needs of our patients at every stage of their young lives —from infancy through adolescence.


Stories of Innovative Pediatric Research

graphic depiction of nanoparticles

The patent for light-emitting nanoparticles will significantly advance CHOC’s research to develop non-invasive treatments for brain injuries.

image depicting a side profile with creative graphics and colors

When the pandemic hit, CHOC’s psychosocial programs for adolescents and young adults with cancer went virtual but brought new opportunities.

Test tubes in a research lab

CHOC and UCI Health’s new designation is expected to attract more resources and recognition to help find novel cures for rare disorders.

graphic representation of genetic material

Families with kids who have rare metabolic disorders are coming from all over the U.S. for investigational gene therapy treatments at CHOC.

child entering MRI machine

Innovators at CHOC pilot augmented reality app that uses CHOC’s mascot, Choco, to explain the MRI process to pediatric patients.

ipad with data and research

With the program’s training, Dr. Sonia Morales will help families fully understand their cancer diagnoses, treatment plan and survivorship roadmap.

twin sisters

CHOC doctors secured a one-time compassionate use FDA approval to use a cutting-edge device to help remove Naomi’s tumor and save her leg.

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baby hope

Before Hope was born, her mom knew she had heart defects and would need surgery after birth. Thankfully, she was in good hands at CHOC.

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CHOC patient and her father

In a first for CHOC, a multidisciplinary team performs deep brain stimulation on 16-year-old to treat her debilitating movement disorder.

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