The purpose of this study is to confirm that the pharmacokinetics of ibrutinib in pediatric participants is consistent with that in adults (part 1) and to assess efficacy (event-free survival [EFS]) of ibrutinib in combination with rituximab, ifosfamide, carboplatin, and etoposide (RICE) or rituximab, vincristine, ifosfamide, carboplatin, and idarubicin (RVICI) background therapy compared to RICE or RVICI background therapy alone (part 2).

Principal Investigator:
​Van Huynh, MD

Research Coordinator:
Dorian Chan
(714) 509-8646

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  • Clinical Trial Info
  • IRB Number: 1711124
  • Sponsor: Janssen Research & Development, LLC
  • Protocol Number: LYM3003
  • NCT Number: NCT02703272
  • Research Type: Lymphoma
  • Phase: III
  • Status: Active - Open to Enrollment