CHOC Children's

CHOC Pressroom

August 13, 2012

As part of a pilot study designed to advance personalized treatment for children and teens battling recurrent cancer, the Hyundai Cancer Institute at CHOC Children’s is the first organization to utilize Illumina’s RapidTrack Whole Genome Sequencing (RapidTrack WGS) service for cancer samples. RapidTrack WGS will enable the study to gather whole genome sequencing data in high depth within 14 days, which is the fastest sample-to-data turnaround time currently offered as a service.  The data generated by Illumina will then by analyzed by the Translational Genomics Research Institute (TGen), another valued partner of the Hyundai Cancer Institute, to provide efficient customized interpretation to the CHOC physicians and researchers, who are part of the hospital’s Molecular Profiling Tumor Board.

Highlighting the project’s impact on patients and their families, the Hyundai Cancer Institute’s Medical Director and principal investigator of the study, Leonard Sender, M.D., says, “We want to be a game changer for patients and their families who are faced with the scary diagnosis of recurrent cancer.  Eighty percent of pediatric cancers are cured, which is wonderful, but we can’t forget about the 20 percent who aren’t.  That vulnerable group is the focus of our efforts, and we are dedicated to providing them with answers and effective treatment as quickly as possible!”

He adds, “We are grateful to our partners, and to Hyundai Motor America and its U.S. dealers, whose grants provided through Hyundai Hope on Wheels® have funded this life-saving research. The ability to rapidly translate samples to data in the lab will have an immediate bedside impact by offering more accurate diagnoses and personalized treatments that save children’s lives.”

According to Dr. Sender, 12 patients are currently enrolled in the study, which underscores the value of whole genomics sequencing as a diagnostic tool to help physicians decide the best course of treatment as quickly as is possible.


Named one of the best children’s hospitals by U.S. News & World Report (2014-2015) and a 2013 Leapfrog Top Hospital for the highest quality of care, Children’s Hospital of Orange County (CHOC Children's) is exclusively committed to the health and well-being of children through clinical expertise, advocacy, outreach, education and research that brings advanced treatment to pediatric patients. Affiliated with the University of California, Irvine, CHOC’s regional health care network includes two state-of-the-art hospitals in Orange and Mission Viejo, many primary and specialty care clinics, a pediatric residency program, and four clinical centers of excellence - the CHOC Children’s Heart, Neuroscience, Orthopaedic and Hyundai Cancer Institutes..

CHOC earned the Gold Level CAPE Award from the California Council of Excellence, the only children’s hospital in California to ever earn this distinction, and was awarded Magnet designation, the highest honor bestowed to hospitals for nursing excellence.  Recognized for extraordinary commitment to high-quality critical care standards, CHOC’s Pediatric Intensive Care Unit (PICU) is the first in the United States to earn the Beacon Award for Pediatric Critical Care Excellence.


Media Contact:
Denise Almazan, Director of Public Relations
phone: (714) 509-8680