CHOC Children's
RESPIRATORY DISORDERS :: Upper Respiratory Disorders

Epiglottitis

What is epiglottitis?

Epiglottitis is an acute life-threatening bacterial infection that results in swelling and inflammation of the epiglottis. (The epiglottis is an elastic cartilage structure at the root of the tongue that prevents food from entering the windpipe when swallowing.) This causes breathing problems, including stridor, that can progressively worsen which may, ultimately, lead to airway obstruction. There is so much swelling that air cannot get in or out of the lungs resulting in a medical emergency.

What causes epiglottitis?

The cause of epiglottitis is a bacterial infection which is spread through the upper respiratory tract. The bacteria usually is Haemophilus influenzae type B (HIB). The reason some children develop the disease, while others do not, is not completely understood. Another bacteria that can cause epiglottitis is group A ß - hemolytic streptococci.

It is important to know that the HIB vaccine, recommended for infants at 2, 4, 6, and 15 to 18 months of age protects against this bacteria, therefore, decreasing the chance of developing epiglottitis.

Facts about epiglottitis:

  • The use of the HIB vaccine has significantly decreased the risk of developing the disease.
  • The disease usually occurs in children 2 to 8 years of age, but has also occurred in adults.
  • The disease can occur at any time; there is no one season that it is more prevalent.

What are the symptoms of epiglottitis?

The symptoms of epiglottitis are similar, regardless of the organism causing the inflammation. The following are the most common symptoms of epiglottitis. However, each child may experience symptoms differently. Symptoms may include:

  • upper respiratory infections (In some children, symptoms of epiglottitis begin with symptoms of an upper respiratory infection.)
  • quick onset of a very sore throat
  • fever
  • muffled voice
  • no cough

As the disease worsens, the following symptoms may appear:

  • drooling
  • unable to talk
  • the child sits leaning forward
  • the child keeps his/her mouth open

How is epiglottitis diagnosed?

Because of the severity of the disease and the need for immediate intervention, the diagnosis is usually made on physical appearance and a thorough medical history. At this point, if epiglottitis is suspected, the child will immediately be transferred to the hospital. As the disease continues, there is a chance of the child's entire airway becoming occluded, (blocked), which can make the child stop breathing.

At the hospital, the following additional tests may be performed to confirm the diagnosis:

  • x-ray of the neck - a diagnostic test which uses invisible electromagnetic energy beams to produce images of internal tissues, bones, and organs onto film.
  • blood tests
  • visualization of the airway - visualization of the airway, under optimal safety conditions by a surgeon in the operating room, may be necessary.

Treatment for epiglottitis:

The treatment for epiglottitis requires immediate emergency care to prevent complete airway occlusion. The child's airway will be closely monitored, and, if needed, the child's breathing will be assisted with machines.

Also, intravenous (IV) therapy with antibiotics will be started immediately. This will help treat the infection by the bacteria. Treatment may also include:

  • steroid medication (to reduce airway swelling)
  • intravenous (IV) fluids, until the child can swallow again

What is the prognosis of epiglottitis?

How well the child recovers from this disease is related to how quickly treatment begins in the hospital setting. Once the child is being monitored, the airway is safe, and antibiotics are started, the disease usually stops progressing within 24 hours. Complete recovery takes longer and depends on each child's condition.

Prevention of epiglottitis:

As mentioned above, epiglottitis caused by the bacteria HIB can be prevented with vaccines that start at the age of 2 months. Epiglottitis caused by other organisms cannot be prevented at this time, but are much less common.

If a child is diagnosed with epiglottitis, the child's family or other close contacts are usually treated with a medication called Rifampin, to prevent the disease in those people who might have been exposed.

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It is important to remember the health information found on this website is for reference only not intended to replace the advice and guidance of your healthcare provider. Always seek the advice of your physician with any questions you may have regarding a medical condition. If you think you may have a medical emergency, call your physician or 911 immediately.

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