MEDICAL GENETICS :: Structural Abnormalities
What are translocations?
The term translocation is used when the location of specific chromosome material changes. There are two main types of translocations: reciprocal and Robertsonian. In a reciprocal translocation, two different chromosomes have exchanged segments with each other:
In a Robertsonian translocation, an entire chromosome attaches to another at the centromere. The centromere is the center part of a chromosome that appears "pinched" between the p and q arms:
This newly formed chromosome is called the translocation chromosome. The translocation in this example is between chromosomes #14 and 21. When a baby is born with this type of translocation chromosome (between #14 and 21), in addition to one normal 14 and two normal 21 chromosomes, the baby will have Down syndrome. This is also called translocation Down syndrome.
Click here to view the
It is important to remember the health information found on this website is for reference only not intended to replace the advice and guidance of your healthcare provider. Always seek the advice of your physician with any questions you may have regarding a medical condition. If you think you may have a medical emergency, call your physician or 911 immediately.
© Children's Hospital of Orange County