CHOC Children's Researcher Detail - Bruce G Nickerson, MD

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Bruce G Nickerson, MD

Dr. Nickerson has staff privileges at CHOC in Orange

Location:
Orange, CA

Specialties:
Pulmonology, Pediatric
Neonatal-Perinatal Medicine

Special Interests:
Cystic fibrosis, preschool asthma, fiberoptic bronchoscopy

Research Focus:
New therapies for cystic fibrosis, noninvasive measurement of gas exchange, and treatment of bronchopulmonary dysplasia

Published Works:

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Office and Contact Information

CHOC Children's Specialists
1201 W La Veta
Suite 201
Orange, CA 92868
phone: (714) 509-8622
fax: (714) 509-3601
map & directions

Web Site:
http://www.choc.org/specialists

Physician / Researcher Bio

Medical Director of CHOC Pulmonary Medicine, Respiratory Therapy and Blood Gas Laboratory Services and Administrative Chief of the CHOC Children's Specialists Division of Pulmonology, Bruce Nickerson M.D. is also Medical Director of the Asthma Chronic Lung Disease collaboration between CHOC and UCI, as well as Medical Co-Director of Pediatric Sub-Acute Services at Whittier Hospital Medical Center. Dr. Nickerson has special expertise in treating cystic fibrosis and providing fiberoptic bronchoscopy. Dr. Nickerson received his MD degree at UCLA and completed both his residency and internship through the University of Arizona in Tucson. He did his fellowship at Children's Hospital of Los Angeles. Dr. Nickerson is board certified in pediatrics, pediatric pulmonology and neonatal perinatal medicine.

As a board certified pediatrician, neonatal-perinatologist, and pediatric pulmonologist, Dr. Nickerson has a variety of clinical interests including cystic fibrosis, chronic lung disease of prematurity, and exercised-induced asthma. He also has great interest in working with children with tracheostomies, preschool asthma, and sleep problems.

Research

Dr. Nickerson’s research interests include new therapies for cystic fibrosis, noninvasive measurement of gas exchange, and treatment of bronchopulmonary dysplasia. In his ongoing work to find new therapies for pediatric patients, he is currently involved in several new cystic fibrosis studies investigating the efficacy of inhaled antibiotics.

Dr. Nickerson has been published in numerous journals including the New England Journal of Medicine, Journal of Pediatrics, American Journal of Respiratory and Critical Care Medicine, Chest, and the Journal of Applied Physics. He has spoken at numerous conferences and symposiums nationally and internationally.

More than 80 CHOC Children's Doctors Named "Physicians of Excellence"
January 03, 2012
More than 80 CHOC Children's physicians, including specialists and pediatricians, are named "Physicians of Excellence" by the Orange County Medical Association....

More than 60 CHOC Children’s Doctors Named “Physicians of Excellence”
January 04, 2011
More than 60 CHOC Children’s physicians, including specialists and pediatricians, are featured as "Physicians of Excellence" in the January 2011 issue of Orange Coast magazine. The "Physicians of Exc...

Published Works

Nickerson BG: The Lung in Sickle Cell Disease. Chapter in Kendig’s Disorders of the Respiratory Tract in Children, 6th Ed. Edited by Victor Chernick, and Thomas Boat. WB Saunders. 2010

Galant SP, Nickerson B Lung function measurement in the assessment of childhood asthma: recent important developments. Curr Opin Allergy Clin Immunol. 2010 Apr; 10(2):149-54

Delfino, RJ, Chang J, Wu J, Ren C, Tjoa T, Nickerson B, Cooper D, Gillen DL Repeated hospital encounters for asthma in children and exposure to traffic-related air pollution near the home. Ann Allergy Asthma Immunol. 2009 Feb;102(2):138-44

Chang J, Delfino RJ, Gillen D, Tjoa T, Nickerson B, Cooper D Repeated respiratory hospital encounters among children with asthma and residential proximity to traffic. Occup Environ Med. 2009 Feb; 66(2):90-8.

Murphy TD, Anbar RD, Lester LA, Nasr SZ, Nickerson B, VanDevanter DR, Colin AA: Treatment with tobramycin solution for inhalation reduces hospitalizations in young CF subjects with mild lung disease. Pediatr Pulmonol. 2004 Oct; 38(4):314-20

Allen J, Zwerdling R, Ehrenkranz R, Gaultier C, Geggel R, Greenough A, Kleinman R, Klijanowicz A, Martinez F, Ozdemir A, Panitch HB, Nickerson B, Stein MT, Tomezsko J, Van Der Anker J; American Thoracic Society. Statement on the care of the child with chronic lung disease of infancy and childhood. Am J Respir Crit Care Med. 2003 Aug1;168(3):356-96

Vichinsky EP, Neumayr LD, Earles AN, Williams R, Lennette ET, Dean D, Nickerson B, Orringer E, McKie V, Bellevue R, Daeschner C, Manci EA. Causes and outcomes of the acute chest syndrome in sickle cell disease. National Acute Chest Syndrome Study Group. N Engl J Med. 2000 June22;342(25):1856-65 Erratum in: N Engl J Med 2000 Sept 14;343(11):824.

Frize M, Wang L, Ennett CM, Nickerson BG, Solven FG, Stevenson M. New advances and validation of knowledge management tools for critical care using classifier techniques. Proc AMIA Symp. 1998:553-7

Nickerson BG: Broncho Pulmonary Dysplasin . Chapter in Essentials of Pediatric Intensive Care, 2nd Ed. Edited by Levin DL and Morris FC, Quality Medical Publishing, Inc. 1410-1415, 1997.

Nickerson BG: Fiberoptic Bronchoscopy. Chapter in Essentials of Pediatric Intensive Care, 2nd Ed. Edited by Levin DL and Morris FC, Quality Medical Publishing, Inc. 170-174, 1997.

Vichinsky EP, Styles LA, Colangelo LH, Wright EC, Castro O, Nickerson B: Acute chest syndrome in sickle cell disease (clinical presentation and course) Cooperative Study of Sickle Cell Disease. Blood, 1997 Mar.

Rogers ZR, and Nickerson BG: Life Threatening Complications in Sickle Cell Disease. Chapter in Essentials of Pediatric Intensive Care 2nd Ed. Edited by Levin DL and Morris FC. Quality Medical Publishing, Inc. 483-487, 1997.

Nickerson BG: Fiberoptic Bronchoscopy. Chapter in Pediatric and Neonatal Tests and Procedures. Edited by Taecusch HW, Christiansen RO, Buescher ES and Hughes. WB Saunders 53-58, 1996.

Nickerson BG: Bronchopulmonary Dysplasia and Family History of Asthma. Pediatric Pulmonology. Editorial Pediatric Pulmonology 20(5):276, 1995 Nov.

Comparison of Three Jet Nebulizer Aerosol Delivery Systems Used to Administer Recombinant Human DNnase I to Patients with Cystic Fibrosis: A report of the Pulmozyme rhDNase Study Group. Chest 108:1; 153-156, 1995.

Nickerson BG, Barnhart SL, and Czervinske MP: Bronchoscopy, Chapter in Perinatal and Pediatric Respiratory Care. Edited by Barnhart SL and Czervinske MP. W.B. Saunders 103-113, 1995.

Nickerson BG: Exercise Testing. Chapter in Respiratory Disease in Children: Diagnosis and Management. Edited by Loughlin GM, Eigen H, Williams and Wilkins, 147-157, 1994.

Fuchs H, Borowitz D, Christiansen D, et al: Effect of Aerosolized Recombinant Human DNase on Exacerbations of Respiratory Symptoms and on Pulmonary Function in Patients with Cystic Fibrosis. New England Journal of Medicine. 331:637-42, 1994.

Kao LC, Durand DJ, McCrea RC, Birch M, Powers RJ and Nickerson BG: Randomized Trial of Long-Term Diuretics for Infants with Oxygen Dependent Bronchopulmonary Dysplasia. J Pediatr 124:772-81, 1994.

Nickerson BG: Emphysema. Chapter in Principles and Practice of Pediatrics, 2nd Edition. Edited by Oski FA, De Angelis CD, Feigin RD, McMillan JA and Warshaw JB, JP Lippincott, 1508-1511, 1994.

Fumey MH, Nickerson BG, Birch M, McCrea R, Kao LC: A Radiographic Method for Estimating Lung Volumes in Sick Infants. Pediatric Pulmonology 13(1):42-47, 1992May.

Nickerson BG: Control of Breathing Problems Associated with Arnold Chiari Malformations in Beckerman RC, Brouillette RT, Hunt CE, Respiratory Control Disorders in Infants and Children. Williams & Wilkins 271-276, 1992.

Boyd JL, Nickerson BG: Pulmonary Management of childhood disabilities in Molnar Gabriella Ed. Physical Medicine and Rehabilitation State of the Art Reviews - The Child with Physical Disability. Hanley & Belfus, Inc. Philadelphia 265-282, 1991.

Fanos J, Nickerson BG: Long term effects of sibling death during adolescence. Journal of Adolescent Research 6:70-82, 1991.

Sivan Y, Arce P, Eigen H, Nickerson BG and Newth CJL: A double blind randomized study of sodium cromoglycate versus placebo in patients with cystic fibrosis and bronchial hyperreactivity, Journal of Allergy and Immunology 85:649-54, 1990.

Durand DJ, Espinoza AM, and Nickerson BG: Association between Prenatal Cocaine Exposure and Sudden Infant Death Syndrome. Journal of Pediatrics 117:909-11, 1990.

Nickerson BG: “Bronchopulmonary Dysplasia: Pathogenesis and Current Therapy. Chapter in “Bronchopulmonary Dysplasia: Strategies for Total Patient Care” Edited by Lund C. Neonatal Network, Berkeley CA 1-15, 1990.

Nickerson BG: Emphysema. Chapter in “Principles and Practice of Pediatrics” Edited by DeAngeles C, Feigin RD, and Warshaw JB. J.B. Lippincott Company, Philadelphia, PA 1376-1378, 1989.

Benton G, Thomas RC, Nickerson BG, McQuitty JC, and Okikawa J: Experience with a metered dose inhaler spacer in the pediatric emergency room. Am J Dis Child 1989 Jun143(6):678-681.

Nickerson BG: Exercise in Children with Asthma. Chapter in “Exercise in Children” edited by Nudel D. Pantel Press, 1989.

Nickerson BG, Commentary on “Iatrogenic epithelial change caused by endotracheal intubation of neonates” by Gau GS, Ryder TA, and Moberly MA, in Yearbook of Pediatrics, Year Book Medical Publishers, Inc., Chicago, IL 1989

Kao LC, Durand DJ, Nickerson BG: Effects of inhaled metaproterenol and atropine on the pulmonary mechanics of infants with bronchopulmonary dysplasia. Pediatric Pulmonology 6:74-80 1989

Nickerson BG: Exercise testing and prescription for the asthmatic patient and those with exercise induced bronchospasm. Chapter in “Exercise in Modern Medicine” Barry A. Franklin, Seymour Gordon, Gerald C. Timmis Eds. Williams & Wilkins, Baltimore MD 1989.

Nickerson BG, Durand DJ, Kao LC: Short-term variability of pulmonary function tests in infants with bronchopulmonary dysplasia. Pediatric Pulmonology 6(1):36-41 1989.

Bar-Yishay E, Bar-Ziv Y, Castile RG, Chernick V, Cooper DM, Godfrey S, Grunstein MM, Kerrebijn KF, Klein M, Nickerson BG, Pasterkamp H, Pederson S, Shannon DC, Silverman M, Tepper RS, Warner JO, Wohl ME, Wood RE. Conference Report Pediatric Pulmonology Workshop, Jerusalem, Israel, March 30-April 2, 1987, Pediatric Pulmonology 4:248-250 1988.

Kao LC, Durand DJ and Nickerson BG: Improving pulmonary function does not decrease oxygen consumption in infants with bronchopulmonary dysplasia. J Pediatrics 112:616-621 1988.

Nickerson BG, Sarkisian C and Tremper K: Bias and Precision of Pulse Oximeters and Arterial Oximeters. Chest 93:515-517 1988.

Nickerson BG, Monaco F: Carbon dioxide electrodes, blood and transcutaneous in “Encyclopedia of Medical Devices and Instrumentation”, John G. Webster Ed., John Wiley & Sons, Inc. July, 1988.

Kao LC, Durand DJ, Phillips BL and Nickerson BG: Oral theophylline and diuretics improve pulmonary mechanics in infants with bronchopulmonary dysplasia. Journal of Pediatrics 111:439-444, 1987.

Nickerson BG: A test for recurrent aspiration in children. Pediatric Pulmonology 3:65-66, 1987.

Nickerson BG: Approach to the wheezing infant. Pediatric Annals 15:99-104, 1986.

Ward SL, Keens TG, Chan LS, Carson SH, Deming DD, Krishna V, MacDonald HM, Martin GI, Meredith KS, Merrit TA, Nickerson BG, Stoddard RA, van der Hal A: Sudden Infant Death in Infants Evaluated by Apnea Programs in California. Pediatrics 77; 451-458, 1986.

Ward SL, Nickerson BG, van der Hal A, Rodriguez AM, Jacobs RA, and Keens TG: Absent hypoxic and hypercapnic arousal responses in children with myelomeningocele and apnea. Pediatrics 78:44-50, 1986.

Nickerson BG: Bronchopulmonary Dysplasia: Chronic lung disease following neonatal respiratory failure. Chest 87:528-535, 1985.

Vichinsky EP, Pennathur-Das R, Nickerson BG, Minor M, Kleman K, Higashino S, and Lubin B: Inadequate erythroid response to hypoxia in cystic fibrosis. Journal of Pediatrics 105:14-21, 1984.

Okikawa J, Phillips B, Nickerson BG: Respiratory support with transcutaneous oxygen and carbon dioxide monitoring for neonatal transports. Journal of the California Perinatal Association. 3 (1) 31-35, 1983.

Scott CB, Nickerson BG, Sargent CW, Platzker ACG, Warburton D, Keens TG: Developmental pattern of maximal transdiaphragmatic pressure in infants during crying. Pediatric Research. 17 (9) 707-709, 1983.

Nickerson BG, Bautista DB, Namey MA, Richards W, and Keens TG: Distance running improves fitness safely in asthmatic children without changes in exercise induced bronchospasm or ventilatory muscle function. Pediatrics 71 (2) 147-12, 1983 Monaco F, McQuitty JC, Nickerson BG: Calibration of a heated transcutaneous CO2 electrode to reflect arterial CO2. American Review of Respiratory Disease. 127 (3) 322-324, 1983

Monaco F, Nickerson BG, McQuitty JC: Continuous transcutaneous oxygen and carbon dioxide monitoring in the pediatric intensive care unit. Critical Care Medicine 10 (11) 765-766, 1982.

Scott CB, Nickerson BG, Dennies P, Platzker AGG, and Keens TG: Diaphragm strength in near miss sudden death syndrome. Pediatrics 69 (6) 782-784, 1982.

Nickerson BG, Keens TG: Measuring ventilatory muscle endurance in man as the sustainable inspiratory pressure. Journal of Applied Physiology: Respiratory, Environmental, and Exercise Physiology 52 (3): 768-772, 1982.

Neustein HB, Nickerson BG, and O’Neal MG: Kartagener’s syndome with absence of inner dyneim arm of respiratory cilia. American Review of Respiratory Diseases 122:859, 1980.

Nickerson BG, Lemen RJ, Gerdes CG, Wegmann MJ, and Robertson GR: Within-subject variability and percent change for significance of spirometry in normal subjects or cystic fibrosis patients. American Review of Respiratory Diseases 122:859, 1980.

Nickerson BG, and Taussig LM: Bronchopulmonary dysplasia: chronic lung disease following neonatal respiratory disorders. Arizona Medicine 36:743, 1979.

Nickerson BG, and Hutter JJ: Opsomyoclonus and neuroblastoma: response to ACTH. Clinical Pediatrics 18:446, 1979.

Nickerson BG, Sahn DJ, Goldberg SJ, and Allen HD: Hazards of inadvertent umbilical venous in catheterization in a patient with anomalous pulmonary venous drainage: a case report. Pediatrics 63:929, 1979.

Nickerson BG: An x-ray diffraction search for conformational changes in DNA at dishwater temperatures. Princeton University Department of Physics undergraduate thesis, under Robert Langridge, PhD, 1972.

Nickerson BG, Partridge RB: The density of intergalactic dust, an upper limit. The Astrophysical Journal 169:203, 1971.