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Nick G Anas, MD

Dr. Anas has staff privileges at CHOC & CHOC at Mission

Orange, CA

Critical Care

Published Works:

Office and Contact Information

CHOC Children's Specialists
1201 W La Veta
Orange, CA 92868
phone: (714) 509-8620
fax: (714) 509-4072
arrow map & directions

Web Site:

Administrative Appointments

  • Pediatrician-In-Chief, CHOC Children’s
  • Medical Director, Pediatric Intensive Care Unit, CHOC Children’s
  • Critical Care, CHOC Children’s Specialist

Academic Appointments

  • Associate Clinical Professor, Pediatrics
    UC Irvine
  • Clinical Professor, Pediatrics
    David Geffen School of Medicine, UCLA

Physician / Researcher Bio

Recognized as an expert in pediatric critical care, Dr. Anas serves as director of the pediatric critical care program at CHOC Children’s. He leads the remarkable team that treats and protects children suffering from acute, life-threatening illnesses and injuries. Dr. Anas has specialized expertise in the treatment of acute respiratory failure, apnea and SIDS.

With more than 25 years of experience, Dr. Anas currently serves as the CHOC pediatrician-in-chief, a position he has held since 2009. Dr. Anas has committed his career to developing and maintaining a critical care program at CHOC defined by clinical excellence and an uncompromising commitment to providing the best care available anywhere in the world to the children and families we serve.

On the forefront of pediatric critical care education and innovative research, Dr. Anas is actively involved in contributing to medical journals and textbooks, and training residents and fellows to be tomorrow’s leaders in the field of pediatric critical care. Dr. Anas has trained many of the medical directors and leaders of pediatric critical care units across the United States.

Through his highly regarded leadership, Dr. Anas has served as a member of the CHOC board of directors and is a member of the board of directors of the CHOC Children’s Specialists, CHOC’s medical foundation. Dr. Anas also serves as a clinical professor of pediatrics for the David Geffen School of Medicine at UCLA and an associate clinical professor of pediatrics at UC Irvine School of Medicine.

Dedicated to clinical excellence, Dr. Anas is board certified in both pediatric critical care medicine and pediatric pulmonology. He completed his fellowship training at the University of Rochester and his pediatric training at the Children’s Medical Center, Southwestern Medical School in Dallas, Texas where he also spent a year as the chief resident. Dr. Anas received his medical degree from the West Virginia University in Morgantown, Virginia. A recognized physician leader, Dr. Anas is consistently named one of Orange County's Top Doctors by the Orange County Medical Association.


  • Medical School
    West Virginia University, Morgantown, W Virginia
  • Medical School - Intern
    Pediatrics, Univ. of Texas Southwestern Medical School
  • Medical School - Resident
    Pediatrics Univ. of Texas Southwestern Medical School
  • Fellowship
    Postdoctoral Fellow in Pediatric Pulmonology and Critical Care
    University of Rochester, School of Medicine, Rochester, New York

Board Certifications

  • Pediatric Critical Care
  • Pediatric Pulmonology

Honors and Awards

  • The Best Doctors in Orange County
    Multiple years
  • UCLA Pediatric Board Review
    Course Lecturer
  • The Best Doctors in America
    Multiple years
  • CHOC Housestaff Teaching Award
    Multiple years
  • Editorial Board, Pediatric Critical Care
    Multiple years

Professional Organizations

  • American Academy of Pediatrics
  • American Thoracic Society
  • California Thoracic Society
  • Society of Critical Care Medicine
  • Orange County Medical Association

Editorial Boards

  • Journal of Pediatrics
  • Pediatric Pulmonology
  • Pediatrics
  • Critical Care Medicine
  • Chest
  • Pediatric Critical Care Medicine
  • British Medical Journal

Lectures and Presentations

  • Pediatrician-in-Chief – Children’s Hospital of Orange County and UCI Irvine Department of Pediatrics 2009.
  • Pulmonary artery catheters: State of the art. Pediatric Cardiac Intensive Care Society 2010
  • Pediatric representative to the Sepsis Advisory Committee. Society of Critical Care Medicine 2010.
  • Appointed to Editorial Board: Pediatric Critical Care Medicine 2010.
  • Cardiopulmonary Interactions: Pediatric Critical Care Board Review Course 2011.
  • President, Children’s Specialty Care Coalition Board of Directors 2012.
  • Board of Directors, Orange County Ronald McDonald House 2012.


Master Campus Plan Update Master Campus Plan Update
Video that describes our recent upgrades to the hospital and talks about our plans for expanding the CHOC campus. Highlights include our new PICU and CVICU units, the new Ambulatory Care Center and Pr ...
Dr. Nick Anas, Director of Pediatric Intensive Care Dr. Nick Anas, Director of Pediatric Intensive Care
Dr. Nick Anas describes that CHOC is here to provide the quality care that the children deserve. ...

CHOC Docs Blog Articles

CHOC Articles & Publications

Dr. Waffarn Retires From Clinical Practice
Physician Connection: Winter 2012
A pioneer in neonatal medicine, Feizal Waffarn, M.D., came to Orange County in 1980, shortly after completing fellowship training at the University of Southern California....
Affiliations Enhance Teaching, Research and Clinical Care
Physician Connection: Fall 2009
In January, CHOC Children's and University of California, Irvine entered into an affiliation that literally changed the delivery of pediatric care in Orange County. In July, in support of the affiliat...
Symposium Showcases CHOC/UC Irvine Expertise
Physician Connection: Fall 2009
The recent CHOC Annual Symposium showcased one of the many benefits of the recent CHOC Children's and University of California, Irvine affiliation: enhanced clinical education....
CHOC Children's Installs New Medical Staff Leadership
Physician Connection: Summer 2009
Change is in the air, both on the world stage and here at home. Our hospitals have new names and medical staff leadership. ...
HOAG Affiliation Enhances Pediatric Care in Coastal Orange County
Physician Connection: Spring 2007
CHOC and Hoag Memorial Hospital Presbyterian have joined forces to enhance and expand pediatric care and services in the coastal Orange County area....
Physician Spotlight: Nick G.Anas, M.D., Medical Director
On The Mark: September 2006
Physician Spotlight: Nick Anas, M.D.
Physician Connection: Fall 2004
In his 20 years at CHOC, Nick Anas, M.D., director of CHOC's Pediatric Intensive Care Unit (PICU), has never grown weary of the enormous challenges the PICU team faces every day....
More Articles...


More than 80 CHOC Children's Doctors Named "Physicians of Excellence"
January 03, 2012
More than 80 CHOC Children's physicians, including specialists and pediatricians, are named "Physicians of Excellence" by the Orange County Medical Association....
CHOC Children's Pediatrician-in-Chief Appointed to Emergency Medical Care Committee
December 20, 2011
CHOC Children's Pediatrician-in-Chief Nick Anas, M.D., was recently appointed to serve on the Emergency Medical Care Committee for Orange County Emergency Medical Services (EMS). The committee advise...
More than 60 CHOC Children’s Doctors Named “Physicians of Excellence”
January 04, 2011
More than 60 CHOC Children’s physicians, including specialists and pediatricians, are featured as "Physicians of Excellence" in the January 2011 issue of Orange Coast magazine. The "Physicians of Exc...
More than 50 CHOC Children's Doctors Named "Physicians of Excellence"
January 04, 2010
The Orange County Medical Association names more than 50 CHOC doctors "Physicians of Excellence."...
CHOC Announces New Physician Leadership
April 14, 2009
CHOC Children's is pleased to announce new physician appointments, which are intended to strengthen the delivery of the healthcare system's tertiary/quaternary pediatric care and to help fulfill the v...
More News...

Published Works

Do T, Chu J, Anas N: Fontan patient with plastic bronchitis treated successfully using aerosolized tissue plasminogen activator: A case report and review of the literature. Pediatr Cardiol 2009; 30: 352-355.

Bronicki R, Anas N: Cardiopulmonary Interaction. Pediatr Crit Care Med 2009; 10: 313-322.

Cvijanovich N, Shanley T, Anas N et al: Validating the genomic signature of septic shock. Physiol Genomics 2008; 34: 127-134.

Wong H, Cvijanovich N, Anas N et al: Identification of pediatric septic shock based on genome-wide expression profiling. BMC Medicine 2009; 7:34.

Wong H, Cvijanovich N, Anas N et al: Genomic expression profiling across the pediatric systemic inflammatory response syndrome, sepsis, and septic shock spectrum. Crit Care Med 2009; 37: 1558-1566.

Gabrail N, Sandler E, Anas N et al: Tropics I: A Phase III, Randomized Double Blind Placebo-Controlled Study of Tenecteplase for Restoration of Function in Central Venous Catheters. J Vasc and Interventional Radiology (submitted for publication).

Bronicki R, Herrera M, Anas N et al: Hemodynamics and cerebral oxygenation following repair of Tetralogy of Fallot: The effects of converting from positive pressure ventilation to spontaneous breathing Congenit Heart Dis 2010; 5:416-421.

McBride J, Anas N: Extracorporeal membrane oxygenation survivors and pulmonary function: Encouraging outcomes early in life. Pediatr Crit Care Med 2010; 12:223-224.

Randolph A, Guo CY, Anas N et al: Vitamin D deficiency is associated with mortality in patients admitted to the pediatric intensive care unit with community acquired influenza infection. JAMA (accepted for publication)

Perkin R, Anas N: Pulmonary artery catheters Pediatr Crit Care Med 2011; 12 (4): 512-20.

Wong H, Cvijonovich N, Anas N et al: Validation of a gene expression-based subclassification strategy for pediatric septic shock. Crit Care Med 2011; 39: 2511-2517.

Randolph A, Vaughn F, Anas N et al: Critically ill children during the 2009-2010 Influenza Pandemic in the United States. Pediatrics 2011; 39: 2511-2517.

Wynn J, Cvijonovich N, Anas N et al: The influence of developmental age on the early transcriptomic response of children with septic shock. Mol Med 2011; 1146-1156.

Kline A, Sorce L, Levin D, Anas N: Pulmonary Disorders in Nursing Care of the Critically Ill Child Hazinski M (Ed). Elsevier USA 2012; 483-561.

Domico M, Ridout D, Bronicki R, Anas N et al: The impact of mechanical ventilation time before initiation of extracorporeal life support on survival in pediatric respiratory failure: A review of the extracorporeal life support registry. Pediatr Crit Care Med 2012: 13:16-21.

Basu R, Stendage S, Anas N et al: Identification of candidate serum biomarkers for severe septic shock – associated kidney injury via microarray. (Submitted for publication).

Wong H, Salibury S, Cvijanovich N et al: The pediatric sepsis biomarker risk model. Critical Care 2012. 16:174


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chocChildren's Hospital of Orange County | UCI University of California, Irvine

Children's Hospital of Orange County is affiliated with UC Irvine Healthcare and UC Irvine School of Medicine

CHOC Children's - 1201 W La Veta Ave, Orange, CA. Phone: 714-997-3000. .